1-(2-(Diethylamino)ethyl)-5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxy-3-methylbenzoyl)-1H-pyrrol-2(5H)-one CAS 370868-85-2
| CAS No. | 370868-85-2 |
| Molecular Formula | C27H33FN2O4 |
| Molecular Weight | 468.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-(2-(Diethylamino)ethyl)-5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxy-3-methylbenzoyl)-1H-pyrrol-2(5H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-(2-(Diethylamino)ethyl)-5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxy-3-methylbenzoyl)-1H-pyrrol-2(5H)-one (CAS 370868-85-2) is a high-purity analytical reference standard with the molecular formula C27H33FN2O4 and a molecular weight of 468.56 g/mol.
Structurally, 1-(2-(Diethylamino)ethyl)-5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxy-3-methylbenzoyl)-1H-pyrrol-2(5H)-one (C27H33FN2O4) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 468.56 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C27H33FN2O4 |
| Molecular Weight | 468.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Diethylamino Standards
- Methyl 4-(1-(2-(diethylamino)ethyl)-3-(3-fluoro-4-methylbenzoyl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-2-yl)benzoate (CAS 618074-17-2)
- 4-[2-[5-[4-(Diethylamino)phenyl]-4,5-dihydro-1-phenyl-1H-pyrazol-3-yl]vinyl]-N,N-diethylaniline (CAS 57609-72-0)
- 1-(2-(Diethylamino)ethyl)-4-(3-fluoro-4-methoxybenzoyl)-3-hydroxy-5-(4-nitrophenyl)-1H-pyrrol-2(5H)-one (CAS 618073-19-1)
- 2-[2-(3-Diethylamino-1-oxo-1H-benzo[f]chromen-2-yl)-vinyl]-6-methoxy-benzoic acid methyl ester (CAS 365542-82-1)
- 1-(2-(Diethylamino)ethyl)-3-hydroxy-4-(4-isopropoxy-3-methylbenzoyl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one (CAS 371125-84-7)
- 6'-(Diethylamino)-2'-(phenylamino)-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one (CAS 29512-46-7)
- Methyl 2-(2-(3-(diethylamino)-1-oxo-1H-benzo[f]chromen-2-yl)ethyl)-6-methoxybenzoate (CAS 365542-83-2)
- 7,7-Bis(4-(diethylamino)-2-methylphenyl)furo[3,4-b]pyrazin-5(7H)-one (CAS 50668-35-4)
Recommended Standards
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- Srt2183 (CAS 1001908-89-9)
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- 1,2-Bis(4-(trifluoromethyl)phenyl)ethane (CAS 42134-71-4)
- Methyl 2,6-Dihydroxybenzoate (CAS 2150-45-0)
- 2-[3-(2-Phenylethyl)-3,4-dihydro[1,3,5]triazino-[1,2-a]benzimidazol-1(2H)-yl]ethanol (CAS 1306739-83-2)
- N-(2-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)pyridin-3-yl)-1,1,1-trifluoromethanesulfonamide (CAS 338411-82-8)
- (Cyclobutylmethyl)(methyl)amine hydrochloride (CAS 1251925-47-9)
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