1,2-Bis(4-(trifluoromethyl)phenyl)ethane CAS 42134-71-4
| CAS No. | 42134-71-4 |
| Molecular Formula | C16H12F6 |
| Molecular Weight | 318.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
1,2-Bis(4-(trifluoromethyl)phenyl)ethane (CAS 42134-71-4), molecular formula C16H12F6 and molecular weight 318.26 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1,2-Bis(4-(trifluoromethyl)phenyl)ethane (C16H12F6) is characterized by fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C16H12F6 |
| Molecular Weight | 318.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Halogen Content | F-containing |
Related Bis Standards
- 1,2-Bis(2-(trifluoromethyl)phenyl)ethane (CAS 287172-66-1)
- 4-((4-(Trifluoromethyl)pyridin-2-yl)oxy)benzenesulfonamide (CAS 1257535-17-3)
- 4-((6-(Trifluoromethyl)pyridin-2-yl)oxy)benzenesulfonamide (CAS 1858256-85-5)
- (2-Oxo-3-(3-(trifluoromethyl)phenyl)oxazolidin-5-yl)methyl methylcarbamate (CAS 64589-75-9)
- 2-((3-(Trifluoromethyl)phenyl)amino)pyridine-3-sulfonic acid (CAS 38025-91-1)
- 4-((3-(Trifluoromethyl)pyridin-2-yl)oxy)benzenesulfonamide (CAS 874839-24-4)
- 4-((5-(Trifluoromethyl)pyridin-2-yl)oxy)benzenesulfonamide (CAS 874839-04-0)
- 4-(5-(4-(Trifluoromethyl)phenyl)-1,2,4-oxadiazol-3-yl)benzaldehyde (CAS 480391-18-2)
Recommended Standards
- 2-(6-(Benzyloxy)hexyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2030409-63-1)
- cis-2-(3-Fluoro-5-(trifluoromethyl)benzoyl)cyclohexanecarboxylic acid (CAS 1443312-34-2)
- 2-(Cyclohexylthio)-N-(3,5-dichlorophenyl)acetamide (CAS 306730-39-2)
- 2-(3-(tert-Butyl)-4-isopropoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1378367-41-9)
- 7-Bromo-6-fluoro-3,4-dihydronaphthalen-2(1h)-one (CAS 1337854-09-7)
- 5-Bromo-N-(1-methylpiperidin-4-yl)pyridin-2-amine (CAS 1096312-60-5)
- (+)-Menthoxyacetic acid (CAS 94133-41-2)
- 1-(4-Methylpyridin-2-yl)propan-2-ol (CAS 937647-99-9)
- 5-Chloro-N-(2-(pyrrolidin-1-yl)ethyl)pyrazine-2-carboxamide (CAS 1160264-34-5)
- N-[4-(4-Methylpiperazin-1-yl)cyclohexyl]acetamide (CAS 1214265-81-2)
- (S)-2,4-dimethyl-3-(thietan-3-ylamino)pentan-2-ol (CAS 1841306-50-0)
- Tert-butyl (3S,4S)-3-bromo-4-hydroxypyrrolidine-1-carboxylate (CAS 252574-02-0)
- 9-(2-bromoethyl)-9H-fluorene (CAS 108012-21-1)
- Tau Peptide (306-336) (Repeat 3 Domain) trifluoroacetate salt (CAS 330456-26-3)
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