5-(4-(tert-Butyl)benzylidene)-2-(4-isopropoxyphenyl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one CAS 371126-97-5
| CAS No. | 371126-97-5 |
| Molecular Formula | C24H25N3O2S |
| Molecular Weight | 419.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 419.54 g/mol gives 5-(4-(tert-Butyl)benzylidene)-2-(4-isopropoxyphenyl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-(4-(tert-Butyl)benzylidene)-2-(4-isopropoxyphenyl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 371126-97-5) is a high-purity analytical reference standard with the molecular formula C24H25N3O2S and a molecular weight of 419.54 g/mol.
The molecular framework of 5-(4-(tert-Butyl)benzylidene)-2-(4-isopropoxyphenyl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (C24H25N3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(4-(tert-Butyl)benzylidene)-2-(4-isopropoxyphenyl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H25N3O2S |
| Molecular Weight | 419.54 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Recommended Standards
- 2-((2-(tert-Butyl)-6,8-dimethyl-5,7-dioxo-5,6,7,8-tetrahydropyrimido[4,5-d]pyrimidin-4-yl)thio)-N-cyclohexylacetamide (CAS 869713-92-8)
- N-({1'-benzyl-4',5'-dimethyl-1'H-[1,2'-bipyrrole]-3'-yl}methyl)benzenesulfonamide (CAS 478077-20-2)
- (Z)-2-(2-(((3,4-dimethoxyphenethyl)imino)methyl)-1H-pyrrol-1-yl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile (CAS 333774-47-3)
- N-(2-Cyano-3-methylbutan-2-yl)-2-((5-phenyl-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 765280-33-9)
- N-acetyl-D-galactosamine-1- (CAS 478518-53-5)
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- (S)-2,6-Diamino-N-((S)-1,6-diamino-1-oxohexan-2-yl)hexanamide (CAS 134276-59-8)
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- Azasetron Impurity 5 (CAS CATO-C4X-28685)
- Semaglutide impurity 77 (CAS CATO-C4X-222677)
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