4-(Trifluoromethylthio)aniline CAS 372-16-7
| CAS No. | 372-16-7 |
| Molecular Formula | C7H6F3NS |
| Molecular Weight | 193.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 4-(Trifluoromethylthio)aniline (C7H6F3NS) contains a nitrile group, sulfur-containing functionality, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 193.19 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 4-(Trifluoromethylthio)aniline (CAS 372-16-7), a certified reference material (molecular formula C7H6F3NS, MW 193.19 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H6F3NS |
| Molecular Weight | 193.19 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Trifluoromethylthio Standards
- 2-(Trifluoromethylthio)aniline (CAS 347-55-7)
- 3-(Trifluoromethylthio)aniline (CAS 369-68-6)
- 4-(Trifluoromethylthio)phenol (CAS 461-84-7)
- 2-(Trifluoromethylthio)toluene (CAS 1736-75-0)
- p-(Trifluoromethylthio)toluene (CAS 352-68-1)
- 6-(Trifluoromethylthio)pyridin-3-ol (CAS 1204234-45-6)
- 6-(Trifluoromethylthio)pyridin-2(1h)-one (CAS 1204234-97-8)
- 6-(Trifluoromethylthio) nicotinonitrile (CAS 1204234-46-7)
Recommended Standards
- For-Phe-OH (CAS 13200-85-6)
- Methyl 3-(5-methoxypyridin-3-yl)acrylate (CAS 1000896-01-4)
- Bz-D-Ala-OH (CAS 17966-60-8)
- 6-Amino-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one (CAS 1002726-62-6)
- N-(2,6-Difluorophenyl)acetamide (CAS 3896-29-5)
- 1-(4,6-Difluoro-1,3,5-triazin-2-yl)-2-methyl-2H-isoindole (CAS 122855-66-7)
- Ethyl1-isopropyl-4,5-dioxopyrrolidine-3-carboxylate (CAS 5336-45-8)
- 2,2-Dimethylcyclopropanecarbonyl chloride (CAS 50675-57-5)
- 2-(5-Methylthiophen-3-yl)butanoic acid (CAS 1495227-86-5)
- 2-Bromophenylhydrazine Hydrochloride (CAS 50709-33-6)
- VIP (6-28) (human, mouse, rat) (CAS 69698-54-0)
- EThyl 4-nitrothiophene-2-carboxylate (CAS 66117-32-6)
- 4-(5-Chloro-3-methyl-1h-pyrazol-1-yl)benzonitrile (CAS 1423029-19-9)
- Semaglutide Impurity 10 (CAS CATO-C4X-222610)
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