Voriconazole Impurity 52 CAS 372-18-9
| CAS No. | 372-18-9 |
| Molecular Formula | C6H4F2 |
| Molecular Weight | 114.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Voriconazole Impurity 52 (CAS 372-18-9), a pharmacopoeial impurity reference standard (molecular formula C6H4F2, MW 114.09 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to fluorine substitution, an aromatic ring system, Voriconazole Impurity 52 is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 114.09 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Voriconazole Impurity 52 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4F2 |
| Molecular Weight | 114.09 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Voriconazole Standards
- Voriconazole Impurity 54 (CAS 2617-47-2)
- Voriconazole EP Impurity C (CAS 137234-88-9)
- Voriconazole Impurity 50 (CAS 79-03-8)
- Voriconazole Impurity 91 (CAS 76686-84-5)
- Voriconazole Impurity 24 (CAS 898044-55-8)
- Voriconazole Impurity 32 (CAS 180287-02-9)
- Voriconazole Impurity 85 (CAS CATO-C4X-136685)
- Voriconazole Impurity 48 (CAS 1403893-61-7)
Recommended Standards
- 201740-95-6 (~13~C_6_)Phenylmethanol DTXSID70584347 (CAS 201740-95-6)
- 1,4-Difluorobenzene (CAS 540-36-3)
- Anisole-Cycle-<SUP>13</SUP>C<SUB>6</SUB> (CAS 152571-52-3)
- 1,2-Difluorobenzene (CAS 367-11-3)
- Flupentixol Impurity 21 (CAS 107265-28-1)
- Cefpirome Impurity 17 (CAS CATO-C4X-120717)
- Relugolix Impurity 157 (CAS CATO-C4X-2429157)
- 5-Bromo-2-thiopheneboronic acid (CAS 162607-17-2)
- Methy 4-chloro-3-fluoro-2-methylbenzoate (CAS 174403-70-4)
- N-methyl-N-(2-(4-(1-(naphthalen-1-ylsulfonyl)-1H-pyrazol-3-yl)phenoxy)ethyl)pyridin-2-amine (CAS 955976-53-1)
- 2-(2,2-Difluoroethyl)-3-methyl-6-oxo-2h,6h,7h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1160246-23-0)
- Propyl 2-(4-chlorophenyl)-1H-benzo[d]imidazole-6-carboxylate (CAS 1416347-12-0)
- 1767AF 5-(3-Fluoro-benzyl)-thiazol-2-ylamine 884497-40-9 C10H9FN2S (CAS 884497-40-9)
- Tirzepatide Impurity 61 (CAS CATO-C4X-324061)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com