3-Methyl-4-(trifluoromethyl)piperidin-4-ol CAS 373604-31-0
| CAS No. | 373604-31-0 |
| Molecular Formula | C7H12F3NO |
| Molecular Weight | 183.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Methyl-4-(trifluoromethyl)piperidin-4-ol (CAS 373604-31-0) is a high-purity analytical reference standard with the molecular formula C7H12F3NO and a molecular weight of 183.17 g/mol.
Structurally, 3-Methyl-4-(trifluoromethyl)piperidin-4-ol (C7H12F3NO) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 1.0, corresponding to approximately 1 ring(s) or double-bond equivalent(s). With a molecular weight of 183.17 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H12F3NO |
| Molecular Weight | 183.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- (4-(Trifluoromethyl)piperidin-4-yl)methanol (CAS 1260809-72-0)
- 4-(trifluoromethyl)azepan-4-ol (CAS 1269532-77-5)
- 6-(trifluoromethyl)-2-pyridyl]methanol (CAS 131747-53-0)
- [2-(trifluoromethyl)-4-pyridyl]methanol (CAS 131747-61-0)
- 2-Ethyl-6-(trifluoromethyl)morpholine (CAS 1375473-87-2)
- (6-(Trifluoromethyl)Piperidin-2-Yl)Methanol (CAS 1784370-07-5)
- (2-(Trifluoromethyl)tetrahydro-2H-pyran-4-yl)methanamine (CAS 1865148-77-1)
- CIS-((6-(TRIFLUOROMETHYL)PIPERIDIN-3-YL)METHANOL (CAS 1932097-26-1)
Recommended Standards
- 3-Methyl-2-(nitromethylene)-2,3-dihydro-1H-imidazole-1-carboximidamide (CAS 7682-01-1)
- 4-(Trifluoromethoxy)cyclohexan-1-amine (CAS 2231674-82-9)
- 3-Amino-5-(trifluoromethyl)cyclohexan-1-ol (CAS 2166735-60-8)
- 4-Acetamido-2-amino-1H-imidazole-5-carboxamide (CAS 959033-09-1)
- 3-(Piperidin-3-ylmethyl)quinoline dihydrochloride (CAS 1187927-46-3)
- 2-(3-Chlorophenyl)-2,3-dihydroquinolin-4(1H)-one (CAS 668998-37-6)
- Diethyl 4,4-(ethyne-1,2-diyl)dibenzoate (CAS 83536-13-4)
- 5-Amino-3-phenyl-3,4-dihydro-2H-pyrrole-4-carboxylic acid (CAS 67159-70-0)
- 4-(Pentane-1-sulfonyl)-butylamine (CAS 1267106-37-5)
- 8-Bromo-7-chloro-4-hydroxy-6-iodo-3-nitroquinolin-2(1H)-one (CAS 2667057-70-5)
- 2-(6,7-Dihydro-4H-thieno[3,2-c]pyran-4-yl)acetic acid (CAS 1258639-48-3)
- N,2-Bis[(4-chlorophenyl)methyl]-1,3-thiazole-4-carboxamide (CAS 478030-48-7)
- Dalilesen impurity 27 (CAS CATO-C4X-301027)
- Autocamtide-2-Related Inhibitory Peptide TFA (CAS 167114-91-2（free base）)
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