3-((2-Fluorophenyl)amino)-2-(4-(3-oxo-3H-benzo[f]chromen-2-yl)thiazol-2-yl)acrylonitrile CAS 374085-30-0
| CAS No. | 374085-30-0 |
| Molecular Formula | C25H14FN3O2S |
| Molecular Weight | 439.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-((2-Fluorophenyl)amino)-2-(4-(3-oxo-3H-benzo[f]chromen-2-yl)thiazol-2-yl)acrylonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-((2-Fluorophenyl)amino)-2-(4-(3-oxo-3H-benzo[f]chromen-2-yl)thiazol-2-yl)acrylonitrile (CAS 374085-30-0), molecular formula C25H14FN3O2S and molecular weight 439.46 g/mol, is a CATO reference standard with documented purity and traceability.
3-((2-Fluorophenyl)amino)-2-(4-(3-oxo-3H-benzo[f]chromen-2-yl)thiazol-2-yl)acrylonitrile (C25H14FN3O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H14FN3O2S |
| Molecular Weight | 439.46 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
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Recommended Standards
- 2,6-Difluoro-N-((3-(naphthalen-2-yl)-1-phenyl-1H-pyrazol-4-yl)methyl)benzamide (CAS 956781-80-9)
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- 1-(3-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)phenyl)-1H-pyrazole-3-carboxylic acid (CAS 2138248-12-9)
- 4-Hydroxy-2-oxo-N'-[(1E)-(2-phenoxyphenyl)methylidene]-1-azatricyclo[7.3.1.0^{5,13}]trideca-3,5(13),6,8-tetraene-3-carbohydrazide (CAS 477868-72-7)
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- 7-Methyl-Indan-1-Ol (CAS 74384-55-7)
- 2-Chloro-3-cyclopropoxy-4-methylpyridine (CAS 1243411-12-2)
- 6-Methyl-1H-pyrrolo[2,3-b]pyridine-2-carbaldehyde (CAS 1427504-16-2)
- 1-(BROMOMETHYL)-N-METHYLCYCLOPROPANECARBOXAMIDE (CAS 1956379-54-6)
- 1-[3-(trifluoromethyl)phenyl]cyclopropan-1-ol (CAS 43187-68-4)
- N'-(3-(1H-pyrrol-1-yl)thiophene-2-carbonyl)-4-fluorobenzenesulfonohydrazide (CAS 672925-21-2)
- (9H-Fluoren-9-yl)methyl(R)-2-methylpiperazine-1-carboxylatehydrochloride (CAS 1187930-83-1)
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