1-[3-(trifluoromethyl)phenyl]cyclopropan-1-ol CAS 43187-68-4
| CAS No. | 43187-68-4 |
| Molecular Formula | C10H9F3O |
| Molecular Weight | 202.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 1-[3-(trifluoromethyl)phenyl]cyclopropan-1-ol (CAS 43187-68-4), a certified reference material (molecular formula C10H9F3O, MW 202.17 g/mol) for analytical method development and quality control.
The molecular framework of 1-[3-(trifluoromethyl)phenyl]cyclopropan-1-ol (C10H9F3O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H9F3O |
| Molecular Weight | 202.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Halogen Content | F-containing |
Related trifluoromethyl Standards
- 1-(2-Methyl-3-(trifluoromethyl)phenyl)ethan-1-one (CAS 1017778-01-6)
- 2-[4-(trifluoromethyl)phenyl]propanal (CAS 103108-04-9)
- (S)-4-(Trifluoromethyl)-2,3-dihydro-1H-inden-1-ol (CAS 1202577-82-9)
- 4-(Trifluoromethyl)-2,3-dihydro-1H-inden-1-ol (CAS 1202577-87-4)
- 1-(Trifluoromethyl)-1-indanol (CAS 121692-27-1)
- 1-[4-(trifluoromethyl)phenyl]cyclopropan-1-ol (CAS 1224883-68-4)
- 2-(Trifluoromethyl)-2,3-dihydro-1H-inden-2-ol (CAS 1250172-63-4)
- (E)-3-(2-(Trifluoromethyl)phenyl)prop-2-en-1-ol (CAS 125617-14-3)
Recommended Standards
- 1-[3-(1,1-Difluoroethyl)-2-fluorophenyl]ethanone (CAS 2359693-44-8)
- 1-[4-(Trifluoromethyl)phenyl]-1-propanone (CAS 711-33-1)
- 1,1,1-Trifluoro-4-phenylbutan-2-one (CAS 86571-26-8)
- 1-Cyclopropyl-3-(trifluoromethoxy)benzene (CAS 2060034-65-1)
- Racemic-2-((2R,3aS,6aS)-5-(tert-butoxycarbonyl)hexahydro-2H-furo[2,3-c]pyrrol-2-yl)acetic acid (CAS 1445951-51-8)
- 2-((2,6-Dichloropyrimidin-4-yl)methyl)isoindoline-1,3-dione (CAS 93512-02-8)
- 2-Bromo-N-[4-(4-morpholinylcarbonyl)phenyl]-acetamide (CAS 926310-51-2)
- (R)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-(3-bromobenzyl)propanoic acid (CAS 1260611-50-4)
- 2-Benzhydryl-5-oxa-2,8-diazaspiro[3.5]Nonan-7-one (CAS 1179337-02-0)
- 4-((Tert-butyldimethylsilyl)oxy)cyclopent-2-en-1-ol (CAS 61305-33-7)
- 4-[(1-Isocyanocyclopropyl)sulfonyl]toluene (CAS 63805-77-6)
- n-(3,4-Dimethoxybenzyl)-3-morpholinopropan-1-amine (CAS 107155-56-6)
- Biotin-PEG4-Amide (CAS 1603854-42-7)
- Palmitoyl Tripeptide -5 ยท 2 TFA (CAS 623172-56-5)
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