Neostigmine Impurity 5 CAS 3743-22-4
| CAS No. | 3743-22-4 |
| Molecular Formula | C8H11NO |
| Molecular Weight | 137.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Neostigmine Impurity 5 (CAS 3743-22-4, C8H11NO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Neostigmine Impurity 5 (C8H11NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 137.18 g/mol, it falls into the low-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Neostigmine Impurity 5 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H11NO |
| Molecular Weight | 137.18 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Related Neostigmine Standards
- Neostigmine EP Impurity B (CAS 99-07-0)
- Neostigmine Impurity 6 (CAS 619-60-3)
- Neostigmine bromide Impurity 14 (CAS 14318-66-2)
- Neostigmine Impurity 21 (CAS 3958-86-9)
- Neostigmine Impurity 24 (CAS 15799-79-8)
- Neostigmine impurity 40 (CAS CATO-C4X-204240)
- Neostigmine Impurity 7 (CAS 611-24-5)
- Neostigmine Impurity N4 (CAS 3483-84-9)
Recommended Standards
- 5-ethyl-2-methylpyrimidin-4-amine (CAS 856974-61-3)
- Elagolix Impurity 41 (CAS 56613-80-0)
- Tiotropium impurity 47 (CAS 4438-38-4)
- 2-Methoxy-5-Methylaniline (CAS 120-71-8)
- Ibuprofen Impurity 112 (CAS CATO-C4X-1082112)
- Roxithromycin EP Impurity K (CAS CATO-C4X-130312)
- Moxifloxacin Impurity 114 (CAS 652-03-9)
- 3-Nitro-3'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxylic acid (CAS 1237091-65-4)
- Amlodipine Besylate EP Impurity E (CAS 140171-65-9)
- N-(4-(dimethylamino)phenyl)methanesulfonamide (CAS 63084-78-6)
- 2-Chloro-N-(6-chloro-1,3-benzothiazol-2-yl)-5-nitrobenzene-1-sulfonamide (CAS 847794-88-1)
- 1-Benzyl-1,2,3,4-tetrahydroquinoxaline dihydrochloride (CAS 2602-38-2)
- 1-(6-(2-Fluorophenoxy)pyridin-3-yl)ethanone (CAS 1555341-04-2)
- Insulin Degludec Impurity 20 (CAS CATO-C4X-215720)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com