5-(Dimethylamino)pyrimidine-2,4(1H,3H)-dione CAS 37454-51-6
| CAS No. | 37454-51-6 |
| Molecular Formula | C20H20Cl2N2O8 |
| Molecular Weight | 487.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-(Dimethylamino)pyrimidine-2,4(1H,3H)-dione (CAS 37454-51-6), molecular formula C20H20Cl2N2O8 and molecular weight 487.29 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 5-(Dimethylamino)pyrimidine-2,4(1H,3H)-dione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 487.29 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 5-(Dimethylamino)pyrimidine-2,4(1H,3H)-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H20Cl2N2O8 |
| Molecular Weight | 487.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dimethylamino Standards
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Recommended Standards
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- Sitagliptin Impurity 25 (CAS CATO-C4X-114425)
- 6-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-2-(4-chlorophenyl)-5H,6H,7H,7aH-pyrrolo[3,4-e][1,3]thiazine-5,7-dione (CAS 337920-07-7)
- 2＇,7＇-Dichlorodihydrofluorescein Diacetate (CAS 4091-99-0)
- 2-Methyl-5-phenyl-1,3-oxazole-4-sulfonyl chloride (CAS 1427380-74-2)
- RIPGBM (CAS 355406-76-7)
- 5-Methylbenzofuran-2-carboxylic Acid (CAS 10242-09-8)
- (S)-2-((1H-indol-3-yl)methyl)-5-(pyrrolidin-3-yl)-1,3,4-oxadiazole (CAS 1234678-93-3)
- 208260-29-1 3-(dimethylamino)-N-(3-(4-hydroxybenzamido)-4-methylphenyl)benzamide N-[5-(3-Dimethylaminobenzamido)-2-methylphenyl]-4-hydroxybenzamide (CAS 208260-29-1)
- 2-(Oxolan-3-yl)-1-phenylethan-1-ol (CAS 1443980-93-5)
- 3-(4H-1,2,4-Triazol-4-yl)aniline (CAS 252928-92-0)
- (4-methyl-5-phenyl-4H-1,2,4-triazol-3-yl)methanol (CAS 881845-15-4)
- all-trans Retinal-d5 (CAS 1217234-58-6)
- (10-31)Semaglutide (CAS CATO-C4X-2226283)
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