trans-3-Hydroxy-4-methylpiperidine CAS 374822-48-7
| CAS No. | 374822-48-7 |
| Molecular Formula | C6H13NO |
| Molecular Weight | 115.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of trans-3-Hydroxy-4-methylpiperidine is closely related to an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies trans-3-Hydroxy-4-methylpiperidine (CAS 374822-48-7), a certified reference material (molecular formula C6H13NO, MW 115.17 g/mol) for analytical method development and quality control.
The molecular framework of trans-3-Hydroxy-4-methylpiperidine (C6H13NO) is characterized by an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), trans-3-Hydroxy-4-methylpiperidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H13NO |
| Molecular Weight | 115.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Related trans Standards
- 5-Hydroxy-2-methylpyridine (CAS 1121-78-4)
- 4-Hydroxy-4-methylpiperidine (CAS 3970-68-1)
- cis-3-Hydroxy-4-methylpiperidine (CAS 955082-92-5)
- 4-Hydroxy-1-methylpiperidine (CAS 106-52-5)
- 2-Hydroxy-4-methylpyridine-d (CAS 916979-13-0)
- (R)-4-Hydroxy-2-piperidinone (CAS 1051316-41-6)
- (S)-3-Hydroxy-1-methylpyrrolidin-2-one (CAS 1292324-56-1)
- 6-Hydroxy-2-piperidinone DISCONTINUED (CAS 1314922-51-4)
Recommended Standards
- trans-3-ethoxycyclobutan-1-amine (CAS 20036-58-2)
- trans-3-Methylpiperidin-4-ol (CAS 227030-11-7)
- trans-3,5-dimethylmorpholine (CAS 67804-26-6)
- trans-3-methyltetrahydropyran-4-amine (CAS 937364-67-5)
- 2-((1H-benzo[d][1,2,3]triazol-1-yl)methyl)-6-methylphenol (CAS 132980-33-7)
- Desmethyl Levofloxacin-d8 Hydrochloride (CAS 1217677-38-7)
- Thiomyristoyl (CAS 1429749-41-6)
- Aztreonam Impurity 2 (CAS CATO-C4X-15222)
- N,N’,N”-Tris(3-aminoquinolino)phosphoric triamide (CAS 2097565-50-7)
- Rac-(3ar,4s,9bs)-8-methyl-3h,3ah,4h,5h,9bh-cyclopenta[c]quinoline-4-carboxylic acid (CAS 1212300-23-6)
- Furfural impurity 6 (CAS CATO-C4X-24886)
- 2-((4-Bromophenyl)(hydroxy)methylene)malononitrile (CAS 1502821-65-9)
- n-(4-(Cyanomethoxy)phenyl)-3,3-dimethylbutanamide (CAS 1015945-26-2)
- Des-Gln19-Tirzepatide (CAS CATO-CPTD788954)
Why CATO?
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