5-Chloro-2-fluoro-3-methylpyridine CAS 375368-84-6
| CAS No. | 375368-84-6 |
| Molecular Formula | C6H5ClFN |
| Molecular Weight | 145.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chloro-2-fluoro-3-methylpyridine is closely related to a nitrile group, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Chloro-2-fluoro-3-methylpyridine (CAS 375368-84-6) is a high-purity analytical reference standard with the molecular formula C6H5ClFN and a molecular weight of 145.56 g/mol.
Based on its molecular formula C6H5ClFN, 5-Chloro-2-fluoro-3-methylpyridine contains a nitrile group, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 145.56 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Chloro-2-fluoro-3-methylpyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5ClFN |
| Molecular Weight | 145.56 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-Chloro-6-(fluoromethyl)pyridine (CAS 1026279-55-9)
- 3-Chloro-2-fluoro-5-methylpyridine (CAS 1031929-23-3)
- 4-Chloro-3-fluoro-2-methylpyridine (CAS 1195251-01-4)
- 5-Chloro-3-fluoro-2-methylpyridine (CAS 1210868-68-0)
- 3-Chloro-6-fluoro-2-methylpyridine (CAS 1214342-64-9)
- 3-Chloro-2-fluoro-4-methylpyridine (CAS 1214377-89-5)
- 4-Chloro-2-fluoro-6-methylpyridine (CAS 1227509-42-3)
- 2-Chloro-4-fluoro-5-methylpyridine (CAS 1227574-24-4)
Recommended Standards
- 5-(Chloromethyl)-2-fluoropyridine (CAS 315180-15-5)
- 6-Chloro-3-fluoro-2-methylpyridine (CAS 884494-78-4)
- 3-(Chloromethyl)-5-fluoropyridine (CAS 39891-37-7)
- 3-Chloro-5-fluoroaniline 3-chloro-5-fluorobenzenamine 4863-91-6 A19644 (CAS 4863-91-6)
- 4-Methyl-2-[(2-methylpentyl)oxy]aniline (CAS 946716-22-9)
- [1,1'-Biphenyl]-4-yl(perfluoroethyl)sulfane (CAS 933673-37-1)
- 7-Fluoro-2,3,4,5-tetrahydrobenzo[b]oxepin-5-amine (CAS 1016689-92-1)
- (S)-2-amino-2-(3-chloro-4-methoxyphenyl)ethan-1-ol (CAS 1213604-59-1)
- 4-hydroxy-5-(trifluoromethyl)pyridine-3-carboxylic acid (CAS 1211530-53-8)
- Ethyl 3-chloro-6-phenyl-4-pyridazinecarboxylate (CAS 34750-70-4)
- Dimetindene Maleate EP Impurity E Hydrochloride (CAS 5143-99-7)
- N-((5-(Thiophene-2-carbonyl)thiophen-2-yl)methyl)thiophene-3-carboxamide (CAS 1421482-80-5)
- 1,4-Bis((4-hydroxyphenyl)amino)anthracene-9,10-dione (CAS 15939-83-0)
- D-Leu26-Tirzepatide (CAS CATO-CPTD788908)
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