6-Fluoro-2-methylnicotinonitrile CAS 375368-85-7
| CAS No. | 375368-85-7 |
| Molecular Formula | 2*C7H5FN2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
6-Fluoro-2-methylnicotinonitrile (CAS 375368-85-7), molecular formula C7H5FN2 and molecular weight 136.13 g/mol, is a CATO reference standard with documented purity and traceability.
6-Fluoro-2-methylnicotinonitrile (C7H5FN2) contains a nitrile group, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | 2*C7H5FN2 |
| Molecular Weight | 136.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- tert-Butyl (6-bromo-5-chloropyridin-2-yl)carbamate (CAS 1263374-39-5)
- 2,5-Diamino-2-methylpentanoic acid (CAS 48047-94-5)
- 7-Bromo-1-isoindolinone (CAS 200049-46-3)
- 5-Benzylidene-2-thioxo-3-(m-tolyl)imidazolidin-4-one (CAS 53865-24-0)
- 2-Methyl-4-oxo-3,4-dihydro-2H-pyrido[1,2-a]pyrimidine-2-carboxylic acid (CAS 339335-11-4)
- N-benzyl-7-methyl-[1,2,4]triazolo[1,5-a]pyridin-5-amine (CAS 1152642-37-9)
- 2-Chloro-N-[4-(2-oxopyrrolidin-1-yl)benzyl]acetamide (CAS 540518-40-9)
- 3-(dimethylamino)-1-[5-[3-(dimethylamino)prop-2-enoyl]-3,4-dimethyl-thieno[2,3-b]thiophen-2-yl]prop-2-en-1-one (CAS 1334660-45-5)
- 1,2:5,6-Di-O-isopropylidene-α-D-ribo-hexofuranose-3-ulose (mixture of keto and ketal forms) (CAS 2847-00-9)
- Semaglutide impurity 55 (CAS CATO-C4X-222655)
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