2-Hydroxy-2-(2,4,5-trifluorophenyl)acetic acid CAS 375369-29-2
| CAS No. | 375369-29-2 |
| Molecular Formula | C8H5F3O3 |
| Molecular Weight | 206.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 2-Hydroxy-2-(2,4,5-trifluorophenyl)acetic acid (C8H5F3O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 206.12 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
2-Hydroxy-2-(2,4,5-trifluorophenyl)acetic acid (CAS 375369-29-2) is a high-purity analytical reference standard with the molecular formula C8H5F3O3 and a molecular weight of 206.12 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Hydroxy-2-(2,4,5-trifluorophenyl)acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5F3O3 |
| Molecular Weight | 206.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Hydroxy Standards
- 4-Hydroxy-2-(trifluoromethoxy)benzaldehyde (CAS 1017083-37-2)
- 2-Hydroxy-4-(trifluoromethoxy)benzaldehyde (CAS 1071156-25-6)
- 2-Hydroxy-6-(trifluoromethyl)nicotinamide (CAS 116548-03-9)
- 3-Hydroxy-4-(trifluoromethoxy)benzaldehyde (CAS 1208078-41-4)
- 2-Hydroxy-2-(2,3,4-trifluorophenyl)acetic acid (CAS 1214332-27-0)
- 5-Hydroxy-2-(trifluoromethyl)benzoic acid (CAS 1243373-31-0)
- 2-Hydroxy-6-(trifluoromethoxy)benzaldehyde (CAS 1261500-70-2)
- 5-Hydroxy-2-(trifluoromethoxy)benzaldehyde (CAS 1261584-14-8)
Recommended Standards
- 2-Hydroxy-2-(2,3,6-trifluorophenyl)acetic acid (CAS 374633-23-5)
- 2-Hydroxy-3-(trifluoromethoxy)benzaldehyde (CAS 497959-31-6)
- 2-amino-6-(Trifluoromethyl)nicotinic acid (CAS 890302-02-0)
- 2-Hydroxy-3-(trifluoromethyl)benzoic acid (CAS 251300-32-0)
- N-cyclopentyl-5-iodopyrimidin-4-amine (CAS 1363405-18-8)
- 3-Bromo-5-((3-(pyrrolidin-1-yl)propyl)amino)benzoic acid (CAS 1990722-54-7)
- 5-(3,4-Dimethoxyphenyl)pyrazine-2,3-dicarbonitrile (CAS 67170-61-0)
- 2-(1-Phenyl-1h-pyrazol-4-yl)acetaldehyde (CAS 545423-93-6)
- 2-(4-Chlorobenzyloxy)benzoyl chloride (CAS 886447-20-7)
- 4-Benzylidene-2-phenyloxazol-5(4H)-one (CAS 842-74-0)
- 6-Amino-N-(5-(1-methylpyrrolidin-2-yl)pyridin-2-yl)hexanamide (CAS 57944-43-1)
- 2'-Chloro-5'-nitro-[1,1'-biphenyl]-3-carbaldehyde (CAS 1242339-09-8)
- 1-(3-Butoxy-4-methoxyphenyl)ethan-1-one (CAS 104249-95-8)
- D-[Arg]30-Semaglutide (CAS CATO-C4X-222653)
Why CATO?
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