1-(o-Tolyl)guanidine CAS 37557-40-7
| CAS No. | 37557-40-7 |
| Molecular Formula | C8H11N3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 185.66 g/mol gives 1-(o-Tolyl)guanidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(o-Tolyl)guanidine (CAS 37557-40-7) is a high-purity analytical reference standard with the molecular formula C8H11N3HCl and a molecular weight of 185.66 g/mol.
1-(o-Tolyl)guanidine (C8H11N3HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(o-Tolyl)guanidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H11N3 HCl |
| Molecular Weight | 185.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related o Standards
- 3-(M-Tolyl)isonicotinic acid (CAS 100004-79-3)
- 2-(m-Tolyl)isonicotinic acid (CAS 100004-94-2)
- 4-(P-tolyl)benzo[b]thiophene-6-carboxylic acid (CAS 100046-86-4)
- 2-((1-(P-tolyl)-3-(trifluoromethyl)-1h-pyrazol-5-yl)oxy)acetohydrazide (CAS 1002034-07-2)
- 1-(O-tolyl)cyclopentan-1-ol (CAS 100256-17-5)
- 5-(p-Tolyl)isoxazole-4-carbonyl chloride (CAS 1003562-04-6)
- 4-(m-Tolyl)-1-tosyl-1H-pyrazol-5-amine (CAS 1003992-23-1)
- 4-(o-Tolyl)-1-tosyl-1H-pyrazol-5-amine (CAS 1003992-24-2)
Recommended Standards
- 2-Chloro-n-(2-cyanoethyl)-n-(4-ethoxyphenyl)acetamide (CAS 852840-54-1)
- 4-(Prop-2-yn-1-yloxy)thiophene-2-carboxylic acid (CAS 1507749-83-8)
- 2-(2,6-Dichlorobenzyl)-5,6-dihydrobenzo[h]cinnolin-3(2H)-one (CAS 383148-05-8)
- Di(pent-4-en-1-yl) succinate (CAS 6624-62-0)
- N3-imino[4-(trifluoromethyl)phenyl]methyl-2,5-dichloronicotinamide (CAS 680216-89-1)
- methyl (1S,3S,5S)-5-methyl-2-azabicyclo[3.1.0]hexane-3-carboxylate;hydrochloride (CAS 2497594-26-8)
- Methyl 4-(isoxazol-5-ylmethoxy)benzoate (CAS 890091-84-6)
- 2H-Indazol-7-amine (CAS 918903-47-6)
- Perylene-3,9-dicarboxylic acid (CAS 6364-19-8)
- Semaglutide Impurity 137 (x TFA Salt) (CAS CATO-C4X-2226137)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com