1-(3-Chloro-4-methoxyphenyl)ethan-1-one CAS 37612-52-5
| CAS No. | 37612-52-5 |
| Molecular Formula | C9H9ClO2 |
| Molecular Weight | 184.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(3-Chloro-4-methoxyphenyl)ethan-1-one (CAS 37612-52-5), molecular formula C9H9ClO2 and molecular weight 184.62 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C9H9ClO2, 1-(3-Chloro-4-methoxyphenyl)ethan-1-one contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 184.62 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(3-Chloro-4-methoxyphenyl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H9ClO2 |
| Molecular Weight | 184.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 2-(3-Chloro-4-methylphenyl)acetic acid (CAS 1000515-63-8)
- 2-(2-chloro-3-methylphenyl)acetic acid (CAS 1000518-49-9)
- 2-Chloro-5-methoxy-4-methylbenzaldehyde (CAS 100948-46-7)
- 2-Chloro-6-(cyclopropylmethoxy)pyrazine (CAS 1019493-28-7)
- 3-Chloro-6-(cyclopropylmethoxy)pyridazine (CAS 1019619-79-4)
- 2-Chloro-6-ethoxybenzaldehyde (CAS 1021230-95-4)
- 3-Chloro-4-methoxybenzimidamide (CAS 102151-35-9)
- 3-Chloro-2-methylbenzhydrazide (CAS 1022873-06-8)
Recommended Standards
- 1-(3-Chloro-4-hydroxyphenyl)propan-2-one (CAS 84023-32-5)
- 1-(3-Chloro-5-methoxyphenyl)ethanone (CAS 214760-34-6)
- 1-(3-Chloro-4-hydroxyphenyl)propan-1-one (CAS 2892-27-5)
- 1-(3-Chlorobenzyl)urea (CAS 76502-61-9)
- 4-((Tert-butoxycarbonyl)amino)-5-phenylpentanoic acid (CAS 790223-54-0)
- Estrone-d4 3-Sulfate Sodium Salt (CAS 285979-80-8)
- N-[(4-Ethylphenyl)methyl]-2,2,4-trimethyl-2,3-dihydro-1-benzofuran-7-amine (CAS 866042-49-1)
- 3-Amino-N-(4-hydroxyphenyl)-N-methylbenzamide (CAS 1322604-62-5)
- Captopril Impurity 8 (CAS 74345-73-6)
- 3β,17,21-Trihydroxy-5α-Pregnane-11,20-dione 21-Acetate (CAS 1856-12-8)
- 4-fluoropyridin-3-amine hydrochloride (CAS 1803603-50-0)
- 1-(6-Bromo-3-(hydroxymethyl)chroman-4-yl)-1-methyl-3-phenylurea (CAS 400089-17-0)
- 3-(Boc-amino)-4-(4-iodophenyl)butyric Acid (CAS 1824505-64-7)
- Galanin (1-13)-Neuropeptide Y (25-36) amide (CAS 147138-51-0)
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