4,6-dichloro-3-nitro-pyridin-2-amine CAS 37660-64-3
| CAS No. | 37660-64-3 |
| Molecular Formula | C5H9Cl2N3O2 |
| Molecular Weight | 214.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4,6-dichloro-3-nitro-pyridin-2-amine (CAS 37660-64-3), a certified reference material (molecular formula C5H9Cl2N3O2, MW 214.05 g/mol) for analytical method development and quality control.
4,6-dichloro-3-nitro-pyridin-2-amine (C5H9Cl2N3O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H9Cl2N3O2 |
| Molecular Weight | 214.05 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related dichloro Standards
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Recommended Standards
- 4,6-Dichloro-1H-indole-2-carbaldehyde (CAS 309718-04-5)
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- 4-Hydroxy-6,7-dichloroquinoline (CAS 203626-51-1)
- Methyl 2-(3-chloropyridin-2-yl)-5-oxopyrazolidine-3-carboxylate (CAS 774600-50-9)
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- 1-Butyl-4-(1-(2-(o-tolyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one (CAS 912896-42-5)
- Methyl (3aR,6aR)-tetrahydro-1H-furo[3,4-c]pyrrole-3a(3H)-carboxylate (CAS 2177263-44-2)
- Proparacaine Impurity 15 (CAS CATO-C4X-202715)
- (Z)-4-(3-(3,5-Dichlorophenyl)-4,4,4-trifluorobut-2-enoyl)-2-methylbenzamide (CAS 943436-66-6)
- (E)-1-Methyl-3-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)vinyl)-1H-pyrazole (CAS 2763275-83-6)
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