Metaraminol Impurity 64 CAS 37661-60-2
| CAS No. | 37661-60-2 |
| Molecular Formula | C12H13NO4 |
| Molecular Weight | 235.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Metaraminol Impurity 64 (C12H13NO4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Metaraminol Impurity 64 (CAS 37661-60-2, C12H13NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Metaraminol Impurity 64 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H13NO4 |
| Molecular Weight | 235.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Nitrogen Atoms | 1 |
Related Metaraminol Standards
- Metaraminol Impurity 59 (CAS CATO-C4X-225259)
- Metaraminol Impurity 16 (CAS 37951-47-6)
- Metaraminol Impurity 96 (CAS CATO-C4X-225296)
- Metaraminol Impurity 103 (CAS CATO-C4X-2252103)
- Metaraminol Impurity (CAS 52618-26-5)
- Metaraminol Impurity 34 (CAS CATO-C4X-225234)
- Metaraminol Impurity 61 (CAS 26607-51-2)
- Metaraminol Impurity 112 (CAS CATO-C4X-2252112)
Recommended Standards
- Darolutamide Impurity 36 (CAS CATO-C4X-310636)
- Ruxolitinib Impurity 102 (CAS CATO-C4X-2058102)
- 2',3'-Dideoxyadenosine (CAS 4097-22-7)
- Cabozantinib Impurity 43 (CAS CATO-C4X-201843)
- Linezolid Impurity 4 (CAS 496031-56-2)
- Vericiguat Impurity 37 (CAS CATO-C4X-289637)
- Estrone Impurity 12 (CAS CATO-C4X-210512)
- 2-(Dimethylamino)-6-(trifluoromethyl)nicotinic acid (CAS 910487-53-5)
- 4-(3-(2-Fluorophenyl)-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one (CAS 1707603-44-8)
- Acotiamide Impurity 46 (CAS CATO-C4X-111446)
- 2-((4-Bromoquinolin-8-yl)oxy)acetonitrile (CAS 88757-34-0)
- 3-Bromo-5-hydroxybenzyl Alcohol (CAS 1020336-51-9)
- Ethyl 2-(1-hydroxycyclopropyl)acetate (CAS 344324-92-1)
- Semaglutide Impurity 143 (CAS CATO-C4X-2226143)
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