Ruxolitinib Impurity 102 CAS CATO-C4X-2058102
| CAS No. | CATO-C4X-2058102 |
| Molecular Formula | C11H13N3O3 |
| Molecular Weight | 235.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Ruxolitinib Impurity 102 (CAS CATO-C4X-2058102), a pharmacopoeial impurity reference standard (molecular formula C11H13N3O3, MW 235.24 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C11H13N3O3, Ruxolitinib Impurity 102 contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 235.24 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Ruxolitinib Impurity 102 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H13N3O3 |
| Molecular Weight | 235.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Ruxolitinib Standards
- Ruxolitinib Impurity 17 (CAS CATO-C4X-205817)
- Ruxolitinib Impurity 171 (CAS 2201066-09-1)
- Ruxolitinib Impurity 38 (CAS 1974336-79-2)
- Ruxolitinib Impurity 47 (CAS CATO-C4X-205847)
- Ruxolitinib Impurity 101 (CAS CATO-C4X-2058101)
- Ruxolitinib Impurity 228 (CAS CATO-C4X-2058228)
- Ruxolitinib impurity 49 (CAS CATO-C4X-205849)
- Ruxolitinib Impurity 12 (CAS CATO-C4X-205812)
Recommended Standards
- Cabozantinib Impurity 43 (CAS CATO-C4X-201843)
- Metaraminol Impurity 59 (CAS CATO-C4X-225259)
- Etomidate impurity 60 (CAS CATO-C4X-188460)
- Metaraminol Impurity 64 (CAS 37661-60-2)
- Posaconazole Impurity 44 (CAS 132962-42-6)
- Nintedanib Impurity 161 (CAS 98953-48-1)
- Cinacalcet Impurity 47 (CAS 82258-76-2)
- 2,6-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-indazole (CAS 1309982-20-4)
- 5-Methoxy-3-(trifluoromethyl)pyridazine (CAS 2231675-13-9)
- 3-Allyl-6-chloro-2-mercaptoquinazolin-4(3h)-one (CAS 49782-31-2)
- 1-(3-chloro-2-fluorophenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1039876-00-0)
- 5-Amino-N-methylbenzo[b]thiophene-2-carboxamide (CAS 1160264-01-6)
- 3-(Phenylethynyl)aniline (CAS 51624-44-3)
- Protein Kinase C (alpha) Peptide (CAS 159939-84-1)
Why CATO?
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