2-Chloro-4,5-dihydroxybenzaldehyde CAS 37686-56-9
| CAS No. | 37686-56-9 |
| Molecular Formula | C7H5ClO3 |
| Molecular Weight | 172.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-4,5-dihydroxybenzaldehyde.
2-Chloro-4,5-dihydroxybenzaldehyde (CAS 37686-56-9), molecular formula C7H5ClO3 and molecular weight 172.57 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 2-Chloro-4,5-dihydroxybenzaldehyde is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 172.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H5ClO3 |
| Molecular Weight | 172.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 3-Chloro-5-methyl-2-nitropyridine (CAS 1210909-07-1)
- 6-Chloro-3-methyl-2-nitropyridine (CAS 1211516-41-4)
- 6-Chloro-5-methyl-3-pyridazinecarboxylic acid (CAS 1211516-60-7)
- 6-Chloro-N-hydroxypyridine-2-carboxamide (CAS 125309-38-8)
- Methyl 5-chloro-3-pyridazinecarboxylate (CAS 1256786-31-8)
- 6-Chloro-N-hydroxynicotinamide (CAS 1263094-64-9)
- 5-Chloro-N-hydroxypicolinamide (CAS 1289026-43-2)
- 6-Chloro-2-methylpyrimidine-4-carboxylic acid (CAS 136518-06-4)
Recommended Standards
- 2-Chloro-3-nitroaniline (CAS 3970-41-0)
- 2-Chloro-4-hydroxybenzoic Acid (CAS 56363-84-9)
- 2-Chloro-3-methyl-5-nitropyridine (CAS 22280-56-4)
- 2-Chloro-4-methyl-3-nitropyridine (CAS 23056-39-5)
- [4-(4-Acetylpiperazin-1-yl)-3-methylphenyl]amine (CAS 862686-09-7)
- N-Ethyl-2-[(4-pentylcyclohexyl)carbonyl]-1-hydrazinecarbothioamide (CAS 866039-98-7)
- 4-Amino-3-chloropicolinic acid (CAS 76165-18-9)
- 3-(3-Pyridinylmethyl)-2-thioxo-1,3-thiazolidin-4-one (CAS 51216-58-1)
- 4-((3-Isopropyl-1H-1,2,4-triazol-5-yl)methoxy)aniline (CAS 1275827-70-7)
- 2-(2-Methyl-imidazol-1-yl)-ethylaminehydrochloride (CAS 167298-64-8)
- 5-Chloro-3-(2,4-dichlorophenyl)-1,2-oxazole-4-carbaldehyde (CAS 1188228-87-6)
- 3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propionic acid (CAS 117017-83-1)
- (2-Methoxy-6-methylphenyl)methanamine hydrochloride (CAS 927902-42-9)
- KALA Amphipathic Peptide (CAS 187987-64-0)
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