(E)-5-amino-3-((3-chloro-2-hydroxy-5-nitrophenyl)diazenyl)-4-hydroxynaphthalene-2,7-disulfonic acid CAS 3769-62-8
| CAS No. | 3769-62-8 |
| Molecular Formula | C16H11ClN4O10S2 |
| Molecular Weight | 518.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-5-amino-3-((3-chloro-2-hydroxy-5-nitrophenyl)diazenyl)-4-hydroxynaphthalene-2,7-disulfonic acid.
(E)-5-amino-3-((3-chloro-2-hydroxy-5-nitrophenyl)diazenyl)-4-hydroxynaphthalene-2,7-disulfonic acid (CAS 3769-62-8), molecular formula C16H11ClN4O10S2 and molecular weight 518.86 g/mol, is a CATO reference standard with documented purity and traceability.
(E)-5-amino-3-((3-chloro-2-hydroxy-5-nitrophenyl)diazenyl)-4-hydroxynaphthalene-2,7-disulfonic acid (C16H11ClN4O10S2) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H11ClN4O10S2 |
| Molecular Weight | 518.86 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related E Standards
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Recommended Standards
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