Norepinephrine Impurity 63 CAS 3770-01-2
| CAS No. | 3770-01-2 |
| Molecular Formula | C9H13NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Norepinephrine Impurity 63 (C9H13NO3HCl) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 219.66 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Norepinephrine Impurity 63 (CAS 3770-01-2, C9H13NO3HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Norepinephrine Impurity 63 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H13NO3 HCl |
| Molecular Weight | 219.66 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Norepinephrine Standards
- Norepinephrine Impurity 50 (CAS 100622-09-1)
- Norepinephrine Impurity 103 (CAS 102743-86-2)
- Norepinephrine EP Impurity F (CAS 103-49-1)
- Norepinephrine Impurity 107 (CAS 112346-92-6)
- Norepinephrine Impurity 28 (CAS 117883-03-1)
- Norepinephrine Impurity 22 (CAS 1197-09-7)
- Norepinephrine Impurity 36 (CAS 121-28-8)
- Norepinephrine Impurity 161 (CAS 1215-29-8（free acid）)
Recommended Standards
- Rimegepant Impurity 57 (CAS CATO-C4X-248757)
- Glipizide EP Impurity E (CAS 66375-96-0)
- Itopride Impurity 5 (CAS 3943-77-9)
- 8-(2-(4-Bromo-2-chlorophenoxy)ethyl)-1,4-dioxa-8-azaspiro[4.5]Decane (CAS 1704080-53-4)
- (S)-2-(4-(trifluoromethyl)phenyl)piperidine (CAS 1228570-26-0)
- (4-AMinophenyl)(2-thienyl)methanone hydrochloride (CAS 2108997-71-1)
- 4-Ethoxy-N,N-dimethylpyrrolo[2,1-f][1,2,4]triazin-2-amine (CAS 175726-70-2)
- 3,5-Dichloro-4-isopropoxyphenol (CAS 1394927-31-1)
- N-[2-(Phenethyloxy)benzyl]-1-phenyl-1-ethanamine (CAS 1040690-43-4)
- Tau Peptide (295-309) trifluoroacetate salt (CAS 330456-46-7)
Why CATO?
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