4-Ethoxy-2,2-bis(trifluoromethyl)thietane CAS 3777-93-3
| CAS No. | 3777-93-3 |
| Molecular Formula | C7H8F6OS |
| Molecular Weight | 254.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-Ethoxy-2,2-bis(trifluoromethyl)thietane (CAS 3777-93-3) is a high-purity analytical reference standard with the molecular formula C7H8F6OS and a molecular weight of 254.19 g/mol.
The molecular framework of 4-Ethoxy-2,2-bis(trifluoromethyl)thietane (C7H8F6OS) is characterized by sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 4-Ethoxy-2,2-bis(trifluoromethyl)thietane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H8F6OS |
| Molecular Weight | 254.19 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
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