1-(2-Ethoxy-3,5-difluorophenyl)-2,2,2-trifluoroethan-1-one CAS 1443304-12-8
| CAS No. | 1443304-12-8 |
| Molecular Formula | C10H7F5O2 |
| Molecular Weight | 254.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(2-Ethoxy-3,5-difluorophenyl)-2,2,2-trifluoroethan-1-one (CAS 1443304-12-8), molecular formula C10H7F5O2 and molecular weight 254.15 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(2-Ethoxy-3,5-difluorophenyl)-2,2,2-trifluoroethan-1-one (C10H7F5O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(2-Ethoxy-3,5-difluorophenyl)-2,2,2-trifluoroethan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7F5O2 |
| Molecular Weight | 254.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
Related Ethoxy Standards
- 1-(4-Ethoxy-3,5-difluorophenyl)-2,2,2-trifluoroethan-1-one (CAS 115467-03-3)
- 1-(3-Ethoxy-4,5-difluorophenyl)-2,2,2-trifluoroethan-1-one (CAS 1443327-55-6)
- 2-(3-(2-(Ethoxy(hydroxy)phosphoryl)ethyl)ureido)acetic acid (CAS 88981-31-1)
- 4-Ethoxy-2,2-bis(trifluoromethyl)thietane (CAS 3777-93-3)
- 3-ethoxy-4-(2-methoxy-2-oxoethoxy)benzoic acid (CAS 1016829-67-6)
- Methyl 2-ethoxy-7-methoxybenzo[d][1,3]dioxole-5-carboxylate (CAS 1093864-55-1)
- Ethyl 2-ethoxy-7-hydroxybenzo[d][1,3]dioxole-5-carboxylate (CAS 733746-42-4)
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Recommended Standards
- 6-Bromo-8-methylquinoline-4-thiol (CAS 1429903-43-4)
- 3-(2,3-Difluorophenyl)-4,4,4-trifluorobutanoic acid (CAS 1409707-29-4)
- 4-(2,2-Difluoroethoxy)-3-trifluoromethylbenzaldehyde (CAS 1486100-65-5)
- 4-(3-Bromophenyl)thiophen-2-amine (CAS 1392042-83-9)
- (S)-2-((tert-Butoxycarbonyl)amino)-3-(4-(dimethylamino)phenyl)propanoic acid (CAS 105115-92-2)
- N-(pyridin-2-ylmethyl)pentan-3-amine (CAS 1020931-58-1)
- 3-(1-Ethyl-5-methyl-1h-pyrazol-4-yl)-1-phenyl-1h-pyrazole-4-carboxylic acid (CAS 1006348-70-4)
- bis[(3-methylphenyl)amino]methane-1-thione (CAS 620-51-9)
- (4-(Butylsulfinyl)phenyl)boronic acid (CAS 1217501-01-3)
- Acetylglycol Salicylate (CAS 87-23-0)
- 3,4-Diethyl-1H-pyrrole-2,5-dione (CAS 34085-07-9)
- 7-Bromo-3H-[1,2,3]triazolo[4,5-b]pyridine (CAS 1781635-60-6)
- 2-(2-Methoxy-4-methylphenoxy)ethan-1-amine (CAS 883541-96-6)
- Insulin Degludec Impurity 20 (CAS CATO-C4X-215720)
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