2-Chloro-4-[trimethylsilylethynyl]pyrimidine CAS 37972-23-9
| CAS No. | 37972-23-9 |
| Molecular Formula | C9H11ClN2Si |
| Molecular Weight | 210.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2-Chloro-4-[trimethylsilylethynyl]pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies 2-Chloro-4-[trimethylsilylethynyl]pyrimidine (CAS 37972-23-9), a certified reference material (molecular formula C9H11ClN2Si, MW 210.74 g/mol) for analytical method development and quality control.
The molecular framework of 2-Chloro-4-[trimethylsilylethynyl]pyrimidine (C9H11ClN2Si) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H11ClN2Si |
| Molecular Weight | 210.74 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- (R)-2-Amino-2-(2-bromo-5-methoxyphenyl)ethan-1-ol (CAS 1213339-89-9)
- 2-Chloro-n-(1,3-dimethyl-1h-pyrazol-5-yl)acetamide (CAS 630120-79-5)
- 5-(methylsulfonylmethyl)thiophene-2-carboxylic acid (CAS 597563-50-3)
- 3-acetamido-4-hydroxybenzene-1-sulfonyl chloride (CAS 81593-03-5)
- N-butyl-4H-1,2,4-triazol-4-amine (CAS 21724-51-6)
- 2-(4-Chlorophenyl)-2-oxoethyl 4-hydroxybenzoate (CAS 386730-85-4)
- Semaglutide impurity 286 (CAS CATO-C4X-2226286)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com