4-Ethynyl-2-(trifluoromethyl)pyrimidine CAS 37972-21-7
| CAS No. | 37972-21-7 |
| Molecular Formula | C7H3F3N2 |
| Molecular Weight | 172.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Ethynyl-2-(trifluoromethyl)pyrimidine (C7H3F3N2) contains a nitrile group, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 4-Ethynyl-2-(trifluoromethyl)pyrimidine (CAS 37972-21-7), a certified reference material (molecular formula C7H3F3N2, MW 172.11 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Ethynyl-2-(trifluoromethyl)pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H3F3N2 |
| Molecular Weight | 172.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Ethynyl Standards
- 5-Ethynyl-2-(trifluoromethyl)pyrimidine (CAS 1196153-54-4)
- 2-Ethynyl-5-(trifluoromethyl)pyrimidine (CAS 1196153-58-8)
- 2-Ethynyl-5-(trifluoromethyl)pyrazine (CAS 1211580-74-3)
- 4-Ethynyl-6-(trifluoromethyl)pyrimidine (CAS 1378258-80-0)
- 2-Ethynyl-4-(trifluoromethyl)pyrimidine (CAS 1698055-59-2)
- 2-Ethynyl-5-nitrobenzonitrile (CAS 1260794-78-2)
- 4-Ethynyl-3-nitrobenzonitrile (CAS 914105-97-8)
- 2-Ethynyl-6-methoxybenzofuran (CAS 1220972-70-2)
Recommended Standards
- 3-acetyl-5-fluoropyrimidine-2,4(1H,3H)-dione (CAS 75410-15-0)
- 4-fluoro-2,3-dihydroxybenzoic acid (CAS 823797-30-4)
- 2-Cyano-3-(trifluoromethyl)pyridine (CAS 406933-21-9)
- 5-(Trifluoromethyl)picolinonitrile (CAS 95727-86-9)
- 2-((2-Chlorobenzyl)thio)-5-phenyl-1,3,4-oxadiazole (CAS 28923-54-8)
- N-(4-(hydrazinylmethyl)phenyl)acetamide (CAS 887596-59-0)
- 2-Fluoro-5-methoxyaniline (CAS 62257-15-2)
- Calcium L-glutamate (CAS 17173-47-6)
- 2-Methoxy-4-nitrophenylboronic Acid (CAS 949892-13-1)
- 3-Bromo-2-(2-ethoxyethoxy)pyridine (CAS 1248439-09-9)
- Pyridoxine Impurity 37 DiHCl (CAS 2726926-28-7)
- 1-(Fluoromethyl)-3-nitrobenzene (CAS 455-94-7)
- 4-Bromo-N-(3-cyanothiophen-2-yl)-2-fluorobenzamide (CAS 1184462-58-5)
- Peptide Impurity 70 TFA Salt (CAS CATO-CPTD788570)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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