2-Chloro-n-(2-chlorophenyl)-5-nitrobenzenesulfonamide CAS 380342-98-3
| CAS No. | 380342-98-3 |
| Molecular Formula | C12H8Cl2N2O4S |
| Molecular Weight | 347.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Chloro-n-(2-chlorophenyl)-5-nitrobenzenesulfonamide (C12H8Cl2N2O4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
2-Chloro-n-(2-chlorophenyl)-5-nitrobenzenesulfonamide (CAS 380342-98-3), molecular formula C12H8Cl2N2O4S and molecular weight 347.17 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Chloro-n-(2-chlorophenyl)-5-nitrobenzenesulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H8Cl2N2O4S |
| Molecular Weight | 347.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-Chloro-n-(4-chlorophenyl)-5-nitrobenzene-1-sulfonamide (CAS 380342-48-3)
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Recommended Standards
- 2-[2,3-Dichloro-4-[(3-hydroxy-2-thienyl)carbonyl]phenoxy]acetic acid (CAS 90966-20-4)
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- N-(4,5-dichloro-2-nitrophenyl)benzenesulfonamide (CAS 1596-36-7)
- Ethyl 3-amino-5-iodobenzo[b]thiophene-2-carboxylate (CAS 1427461-00-4)
- 1-(Chloromethyl)-2-(difluoromethyl)benzene (CAS 1182357-10-3)
- 5-Bromopyrrolo[2,3-c]pyridine-2-carboxylic Acid (CAS 800401-71-2)
- 4,6-Dimethyl-2-nitroaniline (CAS 1635-84-3)
- N-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-sulfonamide (CAS 1416337-90-0)
- Benzo[b]thiophene-3-carboximidamide (CAS 154650-83-6)
- 6-Bromo-2-hydroxy-1-naphthaldehyde (CAS 53815-56-8)
- 5-Methoxy-1-methyl-4,7-dihydro-1H-indole (CAS 17052-38-9)
- 3-Hydrazinylpyridine dHCl (CAS 364727-74-2)
- N-(5-Ethyl-1,3,4-thiadiazol-2-yl)tetradecanamide (CAS 444155-74-2)
- D-Ser32-Tirzepatide (CAS CATO-CPTD788677)
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