(E)-[(2-Chloro-1-methyl-1H-indol-3-yl)methylidene]amino 4-chlorobenzoate CAS 477887-51-7
| CAS No. | 477887-51-7 |
| Molecular Formula | C17H12Cl2N2O2 |
| Molecular Weight | 347.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(E)-[(2-Chloro-1-methyl-1H-indol-3-yl)methylidene]amino 4-chlorobenzoate (CAS 477887-51-7) is a high-purity analytical reference standard with the molecular formula C17H12Cl2N2O2 and a molecular weight of 347.20 g/mol.
The molecular framework of (E)-[(2-Chloro-1-methyl-1H-indol-3-yl)methylidene]amino 4-chlorobenzoate (C17H12Cl2N2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (E)-[(2-Chloro-1-methyl-1H-indol-3-yl)methylidene]amino 4-chlorobenzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H12Cl2N2O2 |
| Molecular Weight | 347.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related E Standards
- 2-Chloro-N-(4-chlorophenyl)-N-(2-formyl-1H-indol-3-yl)acetamide (CAS 182123-52-0)
- (E)-2-chloro-1-methyl-1H-indole-3-carbaldehyde O-(2-chlorobenzoyl) oxime (CAS 477887-41-5)
- (E)-2-chloro-1-methyl-1H-indole-3-carbaldehyde O-(3-chlorobenzoyl) oxime (CAS 477887-40-4)
- 5-Chloro-4-(4-chlorophenoxy)-2-(p-tolyl)pyridazin-3(2H)-one (CAS 551921-41-6)
- 2-Chloro-n-(2-chlorophenyl)-5-nitrobenzenesulfonamide (CAS 380342-98-3)
- 2-Chloro-n-(4-chlorophenyl)-5-nitrobenzene-1-sulfonamide (CAS 380342-48-3)
- 4-Chloro-N-(2-chlorophenyl)-3-nitrobenzene-1-sulfonamide (CAS 26848-43-1)
- 4-Chloro-n-(4-chlorophenyl)-3-nitrobenzenesulfonamide (CAS 248277-40-9)
Recommended Standards
- (5-Bromo-2-methoxyphenyl)methyl (2E)-3-phenylprop-2-enoate (CAS 331460-00-5)
- (E)-1-phenyl-1H-1,2,3-triazole-4-carbaldehyde O-(2,4-dichlorobenzyl) oxime (CAS 338757-39-4)
- (2E)-3-(4-Bromophenyl)-1-(2,5-dimethoxyphenyl)prop-2-en-1-one (CAS 752222-60-9)
- (2E)-1-(4-Bromophenyl)-3-(2,5-dimethoxyphenyl)prop-2-en-1-one (CAS 915032-80-3)
- 4-(3,4-Dimethoxyphenyl)-1-butene (CAS 951891-30-8)
- 7-Chloro-5-[(2-chlorophenyl)methyl]-2,3,4,5-tetrahydro-1,5-benzothiazepin-4-one (CAS 341968-08-9)
- 1-(3-Cyanoquinolin-4-yl)piperidine-4-carboxylic acid (CAS 1156272-06-8)
- TOTU (CAS 136849-72-4)
- Dicresulene (CAS 78480-14-5（free base）)
- 4-Phenyl-N-((tetrahydrofuran-2-yl)methyl)butan-2-amine (CAS 416866-88-1)
- 2-Chloro-6-fluoro-3-methoxyphenylboronic acid pinacol ester (CAS 2121512-16-9)
- Methyl 2-amino-4-fluoro-3-methoxybenzoate (CAS 2092362-15-5)
- 8-Amino-2-methyl-5H-thiazolo[3,2-a]pyridin-5-one (CAS 2387599-31-5)
- Semaglutide impurity 63 (CAS CATO-C4X-222663)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com