Bosutinib Impurity 15 CAS 380843-81-2
| CAS No. | 380843-81-2 |
| Molecular Formula | C25H27Cl2N5O3 |
| Molecular Weight | 516.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Bosutinib Impurity 15 (CAS 380843-81-2) is a certified pharmaceutical impurity reference standard with the molecular formula C25H27Cl2N5O3 and a molecular weight of 516.42 g/mol.
Structurally, Bosutinib Impurity 15 (C25H27Cl2N5O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 516.42 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Bosutinib Impurity 15 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H27Cl2N5O3 |
| Molecular Weight | 516.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Bosutinib Standards
- Bosutinib Impurity 18 (CAS 2468737-92-8)
- Bosutinib Impurity 20 (CAS CATO-C4X-184720)
- Bosutinib Impurity 21 (CAS CATO-C4X-184721)
- bosutinib (CAS 380843-75-4)
- Bosutinib Impurity 1 (CAS 1391063-17-4)
- Bosutinib Impurity 37 (CAS CATO-C4X-184737)
- Bosutinib Impurity 38 (CAS CATO-C4X-184738)
- Bosutinib Impurity 2 (CAS CATO-C4X-18472)
Recommended Standards
- 3-(2,3-dihydrobenzofuran-7-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine (CAS 875639-25-1)
- 1-(Dibutylamino)-3-[1,3-Dichloro-6-(Trifluoromethyl)-9-Phenanthryl]Propane-1,3-Diol (CAS 94133-69-4)
- 1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluoroeicosane 1,1,1,2,2,3,3,4,4,5,5,6,6-tridecakis(fluoranyl)icosane 154628-00-9 A809558 (CAS 154628-00-9)
- 8-Benzyl-4-[3,5-bis(trifluoromethyl)benzoyl]-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326811-04-4)
- Azilsartan Impurity 139 (CAS CATO-C4X-1096139)
- Oxybutynin EP Impurity F (CAS 10399-13-0)
- Imatinib Impurity 40 (CAS CATO-C4X-106840)
- 7-(Oxetan-3-yl)-4,7-diazaspiro[2.5]octane (CAS 1257294-23-7)
- Tripropylene Glycol Monomethyl Ether (CAS 25498-49-1)
- Tert-butyl 6-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate (CAS 1256359-86-0)
- 1-(1-(2,2,2-Trifluoroethyl)-1H-pyrazol-4-yl)-1H-pyrrole-2,5-dione (CAS 1351386-58-7)
- 3-Chloro-1H-pyrazolo[3,4-b]pyridine-4-carbaldehyde (CAS 2034402-69-0)
- 3-Chloro-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1289197-40-5)
- Liraglutide Impurity 28 (CAS CATO-C4X-199228)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com