Bosutinib Impurity 37 CAS CATO-C4X-184737
| CAS No. | CATO-C4X-184737 |
| Molecular Formula | C25H26Cl2N6O4 |
| Molecular Weight | 545.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 545.42 g/mol gives Bosutinib Impurity 37 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Bosutinib Impurity 37 (CAS CATO-C4X-184737, C25H26Cl2N6O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Bosutinib Impurity 37 (C25H26Cl2N6O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Bosutinib Impurity 37 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H26Cl2N6O4 |
| Molecular Weight | 545.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Bosutinib Standards
- Bosutinib Impurity 38 (CAS CATO-C4X-184738)
- Bosutinib Impurity 2 (CAS CATO-C4X-18472)
- Bosutinib Impurity 16 (CAS CATO-C4X-184716)
- Bosutinib Impurity 17 (CAS CATO-C4X-184717)
- Bosutinib Impurity 35 (CAS CATO-C4X-184735)
- bosutinib (CAS 380843-75-4)
- Bosutinib Impurity 1 (CAS 1391063-17-4)
- Bosutinib Impurity 31 (CAS CATO-C4X-184731)
Recommended Standards
- Tazobactam-XTE (CAS CATO-C4X-120523)
- 2-((4-(4-Bromophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-sulfamoylphenyl)acetamide (CAS 477329-42-3)
- Tazobactam Impurity 11 (CAS CATO-C4X-120511)
- 4-(5-Chloro-1-(3-chlorophenyl)-6-oxo-1,6-dihydropyridazin-4-yl)-N-(2-cyano-4,5-dimethoxyphenyl)piperazine-1-carbothioamide (CAS 477867-42-8)
- Cephalexin Impurity 40 (CAS CATO-C4X-126140)
- Carbidopa Impurity 20 (CAS CATO-C4X-231020)
- Oxybutynin Impurity A (CAS CATO-C4X-197212)
- 1-Phenylcyclohexane-1-carboxamide (CAS 2890-60-0)
- 3-Cyclopropyl-6-methoxyisoquinoline (CAS 918662-32-5)
- N-((1H-imidazol-2-yl)methyl)-2-isopropylaniline (CAS 660405-13-0)
- 4-chloro-acetoaceticacimethylester (CAS 32807-28-6)
- 4-(Thiophen-2-ylmethylene)piperidine hydrochloride (CAS 1609578-56-4)
- 2-((3,4-Dichlorobenzyl)thio)-N-methyl-6-((methylthio)methyl)pyrimidin-4-amine (CAS 341965-62-6)
- Myosin Kinase Inhibiting Peptide (CAS 119386-39-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com