Perampanel Impurity 9 CAS 380918-51-4
| CAS No. | 380918-51-4 |
| Molecular Formula | C22H16N2O |
| Molecular Weight | 324.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Perampanel Impurity 9 (C22H16N2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 324.38 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Perampanel Impurity 9 (CAS 380918-51-4), a pharmacopoeial impurity reference standard (molecular formula C22H16N2O, MW 324.38 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H16N2O |
| Molecular Weight | 324.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related Perampanel Standards
- Perampanel impurity 48 (CAS CATO-C4X-243048)
- Perampanel Impurity 1 (CAS 381248-06-2)
- Perampanel Impurity 44 (CAS CATO-C4X-243044)
- Perampanel Impurity 45 (CAS CATO-C4X-243045)
- Perampanel Impurity 31 (CAS CATO-C4X-243031)
- Perampanel Impurity 20 (CAS 2137956-02-4)
- Perampanel Impurity 33 (CAS CATO-C4X-243033)
- Perampanel Impurity 46 (CAS CATO-C4X-243046)
Recommended Standards
- Ribociclib Impurity 32 (CAS CATO-C4X-310032)
- Ruxolitinib Impurity 6 (CAS 1911644-32-0)
- Tert-butyl 4-((4-amino-2-fluorophenoxy)methyl)piperidine-1-carboxylate (CAS 1000053-44-0)
- Ruxolitinib Impurity 27 (CAS CATO-C4X-205827)
- Metformin Impurity 43 (CAS CATO-C4X-1220543)
- Empagliflozin impurity 247 (CAS CATO-C4X-1065247)
- Olopatadine Impurity C504 HBr (CAS 27710-82-3)
- (2R,3R,4S,5R)-2-(2-(4-(2-Hydroxyethyl)-1H-1,2,3-triazol-1-yl)-6-(methylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 906670-54-0)
- Cefixime Impurity 63 (CAS CATO-C4X-113963)
- 4-(Bromomethyl)pyridin-2(1H)-one (CAS 1227585-50-3)
- N-(Benzo[d][1,3]dioxol-5-ylmethyl)-2-((4-methylquinolin-2-yl)thio)acetamide (CAS 671198-81-5)
- (4-cyclopropyl-5-methyl-4H-1,2,4-triazol-3-yl)methanamine dihydrochloride (CAS 1432679-11-2)
- 5α-Pregnan-3α,20α-diol 3-sulfate-D4 (as potassium salt) (CAS CATO-C4X-24431)
- Semaglutide impurity 75 (CAS CATO-C4X-222675)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com