(E)-3-(dimethylamino)-1-(3-(3-fluorophenyl)benzo[c]isoxazol-5-yl)prop-2-en-1-one CAS 383147-84-0
| CAS No. | 383147-84-0 |
| Molecular Formula | C18H15FN2O2 |
| Molecular Weight | 310.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(E)-3-(dimethylamino)-1-(3-(3-fluorophenyl)benzo[c]isoxazol-5-yl)prop-2-en-1-one (CAS 383147-84-0), molecular formula C18H15FN2O2 and molecular weight 310.32 g/mol, is a CATO reference standard with documented purity and traceability.
(E)-3-(dimethylamino)-1-(3-(3-fluorophenyl)benzo[c]isoxazol-5-yl)prop-2-en-1-one (C18H15FN2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (E)-3-(dimethylamino)-1-(3-(3-fluorophenyl)benzo[c]isoxazol-5-yl)prop-2-en-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H15FN2O2 |
| Molecular Weight | 310.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related E Standards
- (2E)-3-(Dimethylamino)-2-[(E)-2-(3-fluorophenoxy)benzoyl]prop-2-enenitrile (CAS 136562-92-0)
- (2E)-3-(Dimethylamino)-1-[3-(4-fluorophenyl)-2,1-benzoxazol-5-yl]prop-2-en-1-one (CAS 321433-31-2)
- N-(4-((6-(Dimethylamino)-9H-purin-9-yl)methyl)phenyl)acetamide (CAS 115204-51-8)
- Ethyl 2-(2-(dimethylamino)pyrimidin-4-yl)-1H-indole-5-carboxylate (CAS 1624260-37-2)
- 1-((2-(Dimethylamino)ethyl)amino)-4-hydroxyanthracene-9,10-dione (CAS 69895-69-8)
- 2-(4-(Dimethylamino)benzyl)-3-oxoisoindoline-4-carboxylic acid (CAS 881041-36-7)
- N-(2-(Dimethylamino)-2-(thiophen-2-yl)ethyl)-2,6-difluorobenzamide (CAS 942000-02-4)
- N-(2-(Dimethylamino)-2-(thiophen-3-yl)ethyl)-2,6-difluorobenzamide (CAS 946373-38-2)
Recommended Standards
- 1-(4-Fluorophenyl)-3-((4-fluorophenyl)sulfonyl)propan-1-one (CAS 477334-49-9)
- (1-(2-(Trifluoromethyl)-1,6-naphthyridin-5-yl)piperidin-4-yl)methanamine (CAS 909644-98-0)
- 2-(4-Fluorophenyl)-N-((5-phenylisoxazol-3-yl)methyl)acetamide (CAS 946340-21-2)
- tert-butyl 3-{[(3-fluorophenyl)carbamoyl]oxy}azetidine-1-carboxylate (CAS 1803580-72-4)
- 1-(4-(4-(4-Methylpiperazine-1-carbonyl)piperidin-1-yl)phenyl)ethan-1-one (CAS 900018-98-6)
- N-methylspiro[2.3]Hexane-1-carboxamide (CAS 1385031-06-0)
- 5-Bromo-2-methyl-1H-pyrrolo[3,2-b]pyridine (CAS 1190318-00-3)
- 3-pyridyl amidoxime (CAS 1594-58-7)
- 1-Bromo-4,5-dichloro-2-fluorobenzene, 97% (CAS 1000572-78-0)
- (S)-N4-Benzyl-2-isobutylpiperazine (CAS 444892-03-9)
- Tert-butyl (piperazin-2-ylmethyl)carbamate (CAS 875551-76-1)
- (S)-1-(3-Chloro-4-nitrophenyl)pyrrolidine-2-carboxylic acid (CAS 230642-98-5)
- N-Methyl-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)methanesulfonamide (CAS 866134-20-5)
- Semaglutide impurity 22(OtBu-Ste-γGlu(OtBu)-AEEA-AEEA-OH) (CAS 1118767-16-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com