Ethyl 1-(5-((3-fluorophenyl)carbamoyl)-1,3,4-thiadiazole-2-carbonyl)piperidine-4-carboxylate CAS 1142210-66-9
| CAS No. | 1142210-66-9 |
| Molecular Formula | C18H19FN4O4S |
| Molecular Weight | 406.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ethyl 1-(5-((3-fluorophenyl)carbamoyl)-1,3,4-thiadiazole-2-carbonyl)piperidine-4-carboxylate (CAS 1142210-66-9), molecular formula C18H19FN4O4S and molecular weight 406.43 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Ethyl 1-(5-((3-fluorophenyl)carbamoyl)-1,3,4-thiadiazole-2-carbonyl)piperidine-4-carboxylate (C18H19FN4O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 406.43 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H19FN4O4S |
| Molecular Weight | 406.43 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Ethyl Standards
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Recommended Standards
- N-(2-methoxybenzyl)-2-(3-(trifluoromethyl)benzyl)thiazole-4-carboxamide (CAS 478042-42-1)
- Bis-(3,4,5-trimethoxyphenyl)-1,3-dioxolane (CAS 116673-45-1)
- 4-Methoxy-N-((4-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)methyl)benzamide (CAS 866018-74-8)
- (E)-N-((1-(3-(Furan-2-yl)acryloyl)piperidin-4-yl)methyl)-4-oxo-4H-chromene-2-carboxamide (CAS 1235674-12-0)
- 2-Amino-1-((S)-3-(benzyl(isopropyl)amino)pyrrolidin-1-yl)propan-1-one (CAS 1354028-84-4)
- N-(3-methoxyphenyl)-3-nitrobenzamide (CAS 107915-06-0)
- 4-Bromo-6,8-difluoro-2-methylquinoline (CAS 1189106-86-2)
- 6-Bromo-4-methoxybenzo[d]oxazole (CAS 2791314-04-8)
- 2-Chloro-3-ethynylpyrazine (CAS 1374115-59-9)
- (2S,4R)-4-(Benzo[b]thiophen-3-ylmethyl)pyrrolidine-2-carboxylic acid (CAS 1049983-80-3)
- 2-(5-Methylpyrazin-2-yl)acetic acid (CAS 431071-67-9)
- Benalfocin hydrochloride (CAS 86129-54-6)
- 4,6-Bis(diphenylphosphino)-10-phenyl-10H-phenoxaphosphine (CAS 261733-09-9)
- Insulin Degludec Impurity 18 (CAS CATO-C4X-215718)
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