(E)-3,4-dihydronaphthalen-1(2H)-one O-(3-(trifluoromethyl)benzoyl) oxime CAS 383148-83-2
| CAS No. | 383148-83-2 |
| Molecular Formula | C18H14F3NO2 |
| Molecular Weight | 333.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (E)-3,4-dihydronaphthalen-1(2H)-one O-(3-(trifluoromethyl)benzoyl) oxime is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(E)-3,4-dihydronaphthalen-1(2H)-one O-(3-(trifluoromethyl)benzoyl) oxime (CAS 383148-83-2) is a high-purity analytical reference standard with the molecular formula C18H14F3NO2 and a molecular weight of 333.30 g/mol.
The molecular framework of (E)-3,4-dihydronaphthalen-1(2H)-one O-(3-(trifluoromethyl)benzoyl) oxime (C18H14F3NO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (E)-3,4-dihydronaphthalen-1(2H)-one O-(3-(trifluoromethyl)benzoyl) oxime meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H14F3NO2 |
| Molecular Weight | 333.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related E Standards
- (E)-3,4-dihydronaphthalen-1(2H)-one O-(3,4-dichlorobenzoyl) oxime (CAS 383148-81-0)
- 3,4-Dihydronaphthalen-1(2H)-one O-((4-methoxyphenyl)sulfonyl) oxime (CAS 145609-81-0)
- (E)-3,4-dihydronaphthalen-1(2H)-one O-((4-chlorophenyl)sulfonyl) oxime (CAS 145609-83-2)
- (E)-3,4-dihydronaphthalen-1(2H)-one O-phenylsulfonyl oxime (CAS 145609-82-1)
- (E)-3,4-dihydronaphthalen-1(2H)-one O-(3-chlorobenzoyl) oxime (CAS 383148-84-3)
- (E)-3,4-dihydronaphthalen-1(2H)-one O-(2-phenylacetyl) oxime (CAS 383148-90-1)
- 3,4-Dihydronaphthalen-1-yl trifluoromethanesulfonate (CAS 123994-49-0)
- 7,8-Dihydronaphthalen-1-yl trifluoromethanesulfonate (CAS 802918-37-2)
Recommended Standards
- (2R,3R,4S,5R)-2-(6-Amino-8-(furan-2-yl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 547765-47-9)
- (R)-2-((tert-Butoxycarbonyl)amino)-3-(2-(trifluoromethyl)phenyl)propanoic acid (CAS 346694-78-8)
- Boc-2-(trifluoromethyl)-L-phenylalanine (CAS 167993-21-7)
- (R)-2-[(tert-Butoxycarbonyl)amino]-3-[4-(trifluoromethyl)phenyl]propanoic Acid (CAS 82317-83-7)
- Dibenzofuran-2-carboxaldehyde (CAS 5397-82-0)
- 3-[[2-(Trimethylsilyl)ethoxy]methyl]-3H-imidazo[4,5-b]pyridine-6-boronic Acid Pinacol Ester (CAS 2005430-90-8)
- Tert-butyl 8-hydroxy-2-azaspiro[5.5]Undecane-2-carboxylate (CAS 2306272-98-8)
- 5H,6H,7H-pyrrolo[2,3-d]pyrimidine-4-carbonitrile (CAS 1578264-12-6)
- Ethyl 3-oxo-5-tosylpentanoate (CAS 1093348-62-9)
- 4-(4-Ethoxyphenyl)-2-{[2-(morpholin-4-yl)ethyl]amino}-4-oxobutanoic acid (CAS 329929-15-9)
- tert-Butyl (2S,4S)-4-amino-2-(2-(tert-butoxy)-2-oxoethyl)piperidine-1-carboxylate (CAS 2667057-26-1)
- Semaglutide impurity 196 (CAS CATO-C4X-2226196)
- N-Nitroso-N-Methyl-N-Hydroxymethylamine (CAS 58840-25-8)
- Semaglutide impurity 199 (CAS CATO-C4X-2226199)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com