2-(4-Fluoronaphthalen-1-yl)acetonitrile CAS 3832-87-9
| CAS No. | 3832-87-9 |
| Molecular Formula | C12H8FN |
| Molecular Weight | 185.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-Fluoronaphthalen-1-yl)acetonitrile.
2-(4-Fluoronaphthalen-1-yl)acetonitrile (CAS 3832-87-9), molecular formula C12H8FN and molecular weight 185.20 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(4-Fluoronaphthalen-1-yl)acetonitrile (C12H8FN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8FN |
| Molecular Weight | 185.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoronaphthalen Standards
- 2-(2-Fluoronaphthalen-1-yl)acetonitrile (CAS 3832-88-0)
- 2-(6-Fluoronaphthalen-2-yl)acetonitrile (CAS 66922-61-0)
- 1-(4-Fluoronaphthalen-1-yl)ethanone (CAS 316-68-7)
- 1-(4-Fluoronaphthalen-1-yl)ethan-1-amine (CAS 1260486-39-2)
- (4-Fluoronaphthalen-2-yl)boronic acid (CAS 1399035-73-4)
- (7-Fluoronaphthalen-1-yl)boronic acid (CAS 1628503-50-3)
- (6-Fluoronaphthalen-2-yl)boronic acid (CAS 1661020-98-9)
- (4-Fluoronaphthalen-1-yl)boronic acid (CAS 182344-25-8)
Recommended Standards
- 2-(2-Fluoro-6-methoxyphenoxy)ethan-1-amine (CAS 914454-97-0)
- 2-(6-Oxo-2-sulfanyl-1,6-dihydropyrimidin-4-yl)acetamide (CAS 868238-02-2)
- 2-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)ethanethioamide (CAS 920510-14-1)
- 2-(Dimethoxymethyl)-3-fluoroaniline (CAS 2244086-00-6)
- 3-[6-(5-aminopent-1-ynyl)-1-oxo-isoindolin-2-yl]piperidine-2,6-dione (CAS 2138440-57-8)
- 2-[5-(2-methyl-1,3-thiazol-4-yl)thien-2-yl]ethanamine (CAS 885526-68-1)
- Methyl 5-bromo-2-nitronicotinate (CAS 1804872-61-4)
- 3-(3-nitrophenyl)-4,5-dihydro-1,2,4-oxadiazol-5-one (CAS 24011-15-2)
- 7-Boc-2-(hydroxymethyl)-1-oxa-7-azaspiro[3.5]nonane (CAS 203662-53-7)
- Prochlorperazine Impurity 12 (CAS 1910-85-6)
- 6-Chloro-2-methoxy-9-phenoxyacridine (CAS 7478-26-4)
- Azilsartan Impurity 27 (CAS 139481-44-0)
- (R)-tert-Butyl 3-(2-chloro-N-ethylacetamido)pyrrolidine-1-carboxylate (CAS 1353998-18-1)
- [Ser]8-Acetylated Semaglutide (CAS CATO-C4X-2226218)
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