2-(Trifluoromethyl)cyclohexane-1-carboxylic acid CAS 384-20-3
| CAS No. | 384-20-3 |
| Molecular Formula | C8H11F3O2 |
| Molecular Weight | 196.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(Trifluoromethyl)cyclohexane-1-carboxylic acid (CAS 384-20-3), molecular formula C8H11F3O2 and molecular weight 196.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(Trifluoromethyl)cyclohexane-1-carboxylic acid (C8H11F3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(Trifluoromethyl)cyclohexane-1-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H11F3O2 |
| Molecular Weight | 196.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Trifluoromethyl Standards
- Ethyl 1-(trifluoromethyl)cyclobutane-1-carboxylate (CAS 1040683-08-6)
- 3-(Trifluoromethyl)cyclohexane-1-carboxylic Acid (CAS 104907-44-0)
- 1-[5-(trifluoromethyl)pyrazin-2-yl]ethanone (CAS 1060812-68-1)
- 6-(trifluoromethyl)piperidine-3-carboxamide (CAS 1155103-12-0)
- cis-4-(Trifluoromethyl)cyclohexanecarboxylic acid (CAS 1202578-27-5)
- Ethyl 2-(trifluoromethyl)cyclobutane-1-carboxylate (CAS 1256483-62-1)
- trans-4-(Trifluoromethyl)cyclohexanecarboxylic Acid (CAS 133261-33-3)
- 1-[2-(trifluoromethyl)pyrimidin-5-yl]ethanone (CAS 1367970-52-2)
Recommended Standards
- 2-(4,4-Difluorocyclohexyl)-2-fluoroacetic acid (CAS 1996761-02-4)
- 2-(Trifluoromethyl)naphthalene (CAS 581-90-8)
- 1H-Imidazole, 1-(2-azidoethyl)-2-methyl-5-nitro- (CAS 60666-28-6)
- 2,5-Pyrazinedicarboxylicacid,dihydrazide (CAS 46321-76-0)
- o-(Methylthio)acetophenone (CAS 1441-97-0)
- Ammonium hexafluorostannate (CAS 16919-24-7)
- 2-Chloro-4-fluoro-5-methylphenol (CAS 1805227-26-2)
- Ampicillin Impurity 38 (CAS CATO-C4X-144338)
- Carvedilol impurity 9 (CAS 1198090-71-9)
- 2-Bromo-3-((4-chlorophenyl)amino)-5,5-dimethylcyclohex-2-en-1-one (CAS 1024132-08-8)
- 3-(3,5-dimethyl-1H-pyrazol-4-yl)-2-methylpropanoic acid (CAS 1093430-18-2)
- Ethyl 3-chlorobut-2-enoate (CAS 38624-62-3)
- 4-(Benzyloxy)-3-methoxyaniline (CAS 15382-71-5)
- Compstatin control peptide (CAS 301544-78-5)
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