7-((4-Chlorophenyl)((3-hydroxypyridin-2-yl)amino)methyl)quinolin-8-ol CAS 385786-48-1
| CAS No. | 385786-48-1 |
| Molecular Formula | C21H16ClN3O2 |
| Molecular Weight | 377.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 7-((4-Chlorophenyl)((3-hydroxypyridin-2-yl)amino)methyl)quinolin-8-ol (CAS 385786-48-1), a certified reference material (molecular formula C21H16ClN3O2, MW 377.82 g/mol) for analytical method development and quality control.
The molecular framework of 7-((4-Chlorophenyl)((3-hydroxypyridin-2-yl)amino)methyl)quinolin-8-ol (C21H16ClN3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-((4-Chlorophenyl)((3-hydroxypyridin-2-yl)amino)methyl)quinolin-8-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H16ClN3O2 |
| Molecular Weight | 377.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
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- 5-(4-Chlorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylic acid (CAS 170571-19-4)
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- N-(5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)-4-(methylsulfonyl)benzamide (CAS 896350-53-1)
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Recommended Standards
- N-(5-chloro-2-methoxyphenyl)-2-(2-(4-ethylphenoxy)acetyl)hydrazine-1-carboxamide (CAS 904197-37-1)
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- Ronifibrate - API Standards (CAS 42597-57-9)
- Baclofen impurity 82 (CAS CATO-C4X-101282)
- Sodium pyridin-4-ylmethanesulfonate (CAS 64794-54-3)
- 6-Chloro-N1-methyl-N1-((tetrahydro-2H-pyran-4-yl)methyl)benzene-1,2-diamine (CAS 1220021-22-6)
- (R)-2-(((4S,5S)-1-methyl-4,5-diphenylimidazolidin-2-ylidene)amino)-3-phenylpropan-1-ol (CAS 210468-90-9)
- (R)-2-(4-ethylphenyl)-2-(methylamino)ethan-1-ol (CAS 1335495-07-2)
- S-(tert-Butyl) 2-((1-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)oxy)ethanethioate (CAS 754983-44-3)
- Methyl 4-aminopiperidine-1-carboxylate (CAS 1187160-88-8)
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-4-[3-(4-methoxyphenyl)-2-methyl-1,2-oxazolidine-5-carbonyl]piperazine (CAS 477864-87-2)
- 3-ethynyl-1,2-dihydropyridin-2-one (CAS 142502-88-3)
- 3-Chloro-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile (CAS 53661-33-9)
- D-Trp25-Tirzepatide (CAS CATO-CPTD788909)
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