5-(4-Chlorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylic acid CAS 170571-19-4
| CAS No. | 170571-19-4 |
| Molecular Formula | C16H12ClN3O4S |
| Molecular Weight | 377.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-(4-Chlorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylic acid (C16H12ClN3O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
5-(4-Chlorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylic acid (CAS 170571-19-4) is a high-purity analytical reference standard with the molecular formula C16H12ClN3O4S and a molecular weight of 377.80 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(4-Chlorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H12ClN3O4S |
| Molecular Weight | 377.80 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
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- N-(5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)-4-(methylsulfonyl)benzamide (CAS 896350-53-1)
- 2-(3-Chlorophenyl)-4-Ethoxy-6-[3-(Trifluoromethyl)Phenyl]Pyridine (CAS 144320-19-4)
- 2-(2-Chlorophenyl)-4-Ethoxy-6-[3-(Trifluoromethyl)Phenyl]Pyridine (CAS 144320-20-7)
- 2-(4-Chlorophenyl)-4-(dimorpholinomethylene)oxazol-5(4H)-one (CAS 61767-52-0)
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- 7-((4-Chlorophenyl)((3-hydroxypyridin-2-yl)amino)methyl)quinolin-8-ol (CAS 385786-48-1)
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Recommended Standards
- 2,5-Dibromo-3-iodopyridin-4-amine (CAS 1227268-81-6)
- 2,6-Dibromo-4-iodophenol (CAS 187407-15-4)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-N-(3-cyanothiophen-2-yl)acetamide (CAS 338777-50-7)
- (1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidin-4-yl)(morpholino)methanone (CAS 303150-14-3)
- Sodium 1-methyl-5-(trifluoromethyl)-1H-pyrazole-4-sulfinate (CAS 2137679-15-1)
- 4-(4-Amino-2,5-dimethoxyphenyl)-2,5-dimethoxyaniline hydrochloride (CAS 1235439-32-3)
- 2-(3-Cyanophenoxy)-N-(2,2,2-trifluoroethyl)acetamide (CAS 793677-47-1)
- 5-(Hydroxymethyl)isoquinolin-1(2H)-one (CAS 1184917-29-0)
- 1-((2-Methoxyphenyl)amino)cyclohexanecarboxylic acid (CAS 725252-87-9)
- 2-Phenylimidazo[2,1-a]isoquinoline (CAS 70845-68-0)
- (R)-2-(2,3-dichlorophenyl)-2-(methylamino)ethan-1-ol (CAS 1335596-07-0)
- 1-(4-(Trifluoromethyl)phenyl)pyrrolidin-2-one (CAS 188622-31-3)
- 5-Chloro-2-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazole (CAS 1361380-49-5)
- Semaglutide impurity 42 (CAS CATO-C4X-222642)
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