Ritonavir Impurity 42 CAS 38585-74-9

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.38585-74-9
Molecular FormulaC4H5NOS
Molecular Weight115.15 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ritonavir Impurity 42 CAS 38585-74-9 chemical structure

Description

As a process- or degradation-related impurity, Ritonavir Impurity 42 (CAS 38585-74-9, C4H5NOS) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Owing to an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, Ritonavir Impurity 42 is typically white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 115.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Ritonavir Impurity 42 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC4H5NOS
Molecular Weight115.15 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1968
Nitrogen Atoms1
Sulfur Atoms1

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