4-Hydroxyquinoline-8-carboxylic Acid CAS 386207-63-2
| CAS No. | 386207-63-2 |
| Molecular Formula | C10H7NO3 |
| Molecular Weight | 189.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-Hydroxyquinoline-8-carboxylic Acid (CAS 386207-63-2), molecular formula C10H7NO3 and molecular weight 189.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Hydroxyquinoline-8-carboxylic Acid (C10H7NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H7NO3 |
| Molecular Weight | 189.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Related Hydroxyquinoline Standards
- 7-Hydroxyquinoline-4-carboxylic acid (CAS 1017969-32-2)
- 6-Hydroxyquinoline-3-carboxylic acid (CAS 1137826-05-1)
- 7-Hydroxyquinoline-8-carboxylic acid (CAS 1146298-53-4)
- 4-Hydroxyquinoline-7-carboxylic acid (CAS 1150618-22-6)
- 3-Hydroxyquinoline-4-carboxylic acid (CAS 118-13-8)
- 7-Hydroxyquinoline-6-carboxylic acid (CAS 1227608-04-9)
- 3-Hydroxyquinoline-6-carboxylic acid (CAS 1233244-78-4)
- 6-Hydroxyquinoline-7-carboxylic acid (CAS 1261434-11-0)
Recommended Standards
- 4-Hydroxyquinazoline-7-carboxamide (CAS 954803-07-7)
- 4-Isonicotinoyl-1H-imidazol-2(3H)-one (CAS 88166-66-9)
- 4-Hydroxyisoquinoline-7-carboxylic acid (CAS 2506275-15-4)
- 4-Methyl-8-nitrocinnoline (CAS 20864-29-3)
- 5-Methylcotinine-d3 (CAS 1217003-12-7)
- 1-(3-(Trifluoromethyl)pyridin-4-yl)cyclopropane-1-carboxylic acid (CAS 1427024-73-4)
- (Z)-[(4-Chlorophenyl)methoxy]({2-[4-(4-methoxyphenyl)piperazin-1-yl]-1-phenylethylidene})amine (CAS 338396-69-3)
- 3-Fluoro-N-(pyridin-2-ylmethyl)-N-(thiophen-3-ylmethyl)benzamide (CAS 1235389-97-5)
- 2-Phenyl-1H-indol-6-ol (CAS 62613-58-5)
- Benzyl 3-chloropiperidine-1-carboxylate (CAS 1353965-30-6)
- 26706-11-6 1-(2-Chloroethyl)-1H-benzimidazole hydrochloride MFCD22422018 (CAS 26706-11-6)
- Benzoic acid, 4-ethenyl-, 2,5-dioxo-1-pyrrolidinyl ester (CAS 97856-35-4)
- Fenofibrate Impurity N113 (CAS 60012-96-6)
- Peptide Impurity 15 (CAS 1227750-69-7)
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