4-Chloroquinoline-6-carboxylic acid CAS 386207-77-8
| CAS No. | 386207-77-8 |
| Molecular Formula | C10H6ClNO2 |
| Molecular Weight | 207.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Chloroquinoline-6-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-Chloroquinoline-6-carboxylic acid (CAS 386207-77-8), a certified reference material (molecular formula C10H6ClNO2, MW 207.61 g/mol) for analytical method development and quality control.
The molecular framework of 4-Chloroquinoline-6-carboxylic acid (C10H6ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloroquinoline-6-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H6ClNO2 |
| Molecular Weight | 207.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloroquinoline Standards
- 2-Chloroquinoline-5-carboxylic Acid (CAS 1092287-30-3)
- 2-Chloroquinoline-7-carboxylic acid (CAS 1092287-40-5)
- 8-Chloroquinoline-4-carboxylic acid (CAS 121490-66-2)
- 8-chloroquinoline-5-carboxylic acid (CAS 121490-68-4)
- 3-Chloroquinoline-8-carboxylic acid (CAS 125300-42-7)
- 7-Chloroquinoline-4-carboxylic Acid (CAS 13337-66-1)
- 5-Chloroquinoline-3-carboxylic Acid (CAS 1416439-55-8)
- 4-Chloroquinoline-2-carboxylic acid (CAS 15733-82-1)
Recommended Standards
- 4-(5-Oxazoyl)benzoyl chloride (CAS 679807-12-6)
- 4-Chloroquinoline-7-carboxylic Acid (CAS 49713-58-8)
- 3-Mesitylpropanoic acid (CAS 7250-66-0)
- 4-Chloroquinoline-8-carboxylic acid (CAS 216257-37-3)
- 2-Methyl-9-phenoxyacridine (CAS 61078-24-8)
- (3AS,6R)-2-(4-isopropylphenyl)-1-oxo-1,2,3,6,7,7a-hexahydro-3a,6-epoxyisoindole-7-carboxylic acid (CAS 956816-51-6)
- 1-Ethyl-5-fluoro-1H-1,3-benzodiazol-2-amine (CAS 1155599-04-4)
- 4-(Difluoromethyl)-3-fluoropicolinic acid (CAS 1805307-17-8)
- 3-Ethyl-2-Methyl-2-(3-Methylbutyl)-Oxazolidine (CAS 143860-04-2)
- 7-Bromo-5-methyl-1H-indazole (CAS 885272-97-9)
- 1-[(5-methylfuran-2-yl)carbonyl]piperazine hydrochloride (CAS 1240526-42-4)
- Methyl 4'-(acetylamino)[1,1'-biphenyl]-4-carboxylate (CAS 54643-72-0)
- 2-Phenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 879291-27-7)
- Semaglutide impurity 56 (CAS CATO-C4X-222656)
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