4-(4-Chlorophenyl)thiophene-2-carboxylicacid CAS 386715-46-4

Purity 97%+In StockPharmaceutical Standards
CAS No.386715-46-4
Molecular FormulaC11H7ClO2S
Molecular Weight238.69 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(4-Chlorophenyl)thiophene-2-carboxylicacid CAS 386715-46-4 chemical structure

Description

As a certified reference material (CRM), 4-(4-Chlorophenyl)thiophene-2-carboxylicacid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

4-(4-Chlorophenyl)thiophene-2-carboxylicacid (CAS 386715-46-4), molecular formula C11H7ClO2S and molecular weight 238.69 g/mol, is a CATO reference standard with documented purity and traceability.

4-(4-Chlorophenyl)thiophene-2-carboxylicacid (C11H7ClO2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC11H7ClO2S
Molecular Weight238.69 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Sulfur Atoms1

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