Ibuprofen EP Impurity E CAS 38861-78-8

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.38861-78-8
Molecular FormulaC12H16O
Molecular Weight176.25 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ibuprofen EP Impurity E CAS 38861-78-8 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

As a process- or degradation-related impurity, Ibuprofen EP Impurity E (CAS 38861-78-8, C12H16O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Ibuprofen EP Impurity E (C12H16O) contains a hydroxyl group, an ether linkage, an aromatic ring system. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC12H16O
Molecular Weight176.25 g/mol
Purity>95%
StorageStore at 2-8°C
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityStable under recommended storage conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1968

Related Ibuprofen Standards

Recommended Standards

Why CATO?