Ibuprofen EP Impurity K CAS 43153-07-7
| CAS No. | 43153-07-7 |
| Molecular Formula | C10H10O3 |
| Molecular Weight | 178.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ibuprofen EP Impurity K under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Ibuprofen EP Impurity K (CAS 43153-07-7, C10H10O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Ibuprofen EP Impurity K is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 178.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C10H10O3 |
| Molecular Weight | 178.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
Related Ibuprofen Standards
- Ibuprofen Impurity 73 (CAS 25329-47-9)
- Ibuprofen EP Impurity N (CAS 3585-52-2)
- Ibuprofen EP Impurity N (CAS CATO-C4X-1082154)
- Ibuprofen Impurity 61 (CAS 38861-88-0)
- Ibuprofen EP Impurity Q (CAS 36039-35-7)
- Ibuprofen Impurity 56 (CAS CATO-C4X-108256)
- Ibuprofen Impurity 23 (CAS 7645-81-0)
- Ibuprofen EP Impurity E (CAS 38861-78-8)
Recommended Standards
- Donepezil Impurity 18 (CAS 90843-62-2)
- Bisoprolol Impurity 36 (CAS 14697-49-5)
- Donepezil Impurity 17 (CAS 127399-78-4)
- Ipratropium Impurity 11 (CAS 5894-79-1)
- Lacosamide EP Impurity E(R-Isomer) (CAS 175481-39-7)
- Diazoxide impurity 5 (CAS 19185-77-4)
- Entacapone Impurity 26 (CAS 672-13-9)
- 50606-97-8 Benzoyl chloride, 4-octyl- 4-Octylbenzoyl chloride EINECS 256-649-7 (CAS 50606-97-8)
- 1-HEXADECYL-4-PHENYLPYRIDINIUM BROMIDE (CAS 123482-18-8)
- tert-Butyl ((S)-4-hydroxy-3-oxo-1-((S)-2-oxopyrrolidin-3-yl)butan-2-yl)carbamate (CAS 2755783-76-5)
- Ribavirin Impurity 51 (CAS 4928-88-5)
- 10-Camphorsulfonic Acid Ethyl Ester (CAS 108481-13-6)
- 1-(But-3-yn-1-yl)imidazolidin-2-one (CAS 928830-21-1)
- Antifreeze Polypeptide 6 (winter flounder) trifluoroacetate salt (CAS 122604-16-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com