Lamotrigine EP Impurity G CAS 38943-76-9
| CAS No. | 38943-76-9 |
| Molecular Formula | C9H7Cl2N5 |
| Molecular Weight | 256.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Lamotrigine EP Impurity G (CAS 38943-76-9), a pharmacopoeial impurity reference standard (molecular formula C9H7Cl2N5, MW 256.09 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Lamotrigine EP Impurity G (C9H7Cl2N5) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 256.09 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Lamotrigine EP Impurity G under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H7Cl2N5 |
| Molecular Weight | 256.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Lamotrigine Standards
- Lamotrigine 6-(3,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine Impurity (CAS 36518-85-1)
- Lamotrigine EP Impurity B and Lamotrigine EP Impurity C (CAS 84689-20-3)
- Lamotrigine Impurity 10 (CAS 77668-43-0)
- Lamotrigine Impurity 2 (CAS 94266-27-0)
- Lamotrigine EP Impurity B (CAS 94213-24-8)
- Lamotrigine EP Impurity C (CAS 94213-23-7)
- Lamotrigine (CAS 84057-84-1)
- Lamotrigine Impurity 15 (CAS 1373393-59-9)
Recommended Standards
- 1-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone (CAS 58905-16-1)
- Anagrelide (CAS 68475-42-3)
- N2-(2,4-Dichlorophenyl)-1,3,5-triazine-2,4-diamine (CAS 6975-84-4)
- Irsogladine Impurity 1 (CAS CATO-C4X-29141)
- Bromhexine impurity 54 (CAS CATO-C4X-106054)
- Mitiglinide Impurity 11 (CAS CATO-C4X-116111)
- Loxoprofen impurity 119 (CAS CATO-C4X-1488119)
- 5-Nitro-1,10-phenanthrolineferroussulfate (CAS 23700-19-8)
- Z-Val-Glu(OMe)-Ile-DL-Asp(OMe)-fluoromethylketone (N-1945.0005) (CAS 1926163-62-3)
- (9Z,12E)-Hexadeca-9,12-dienoic acid (CAS 5070-03-1)
- 1-Bromo-2-fluorocyclopropane (CAS 1185112-51-9)
- Methyl 3-Bromo-1-methylindole-6-carboxylate (CAS 1186663-45-5)
- (4-(1-(Trifluoromethyl)cyclopropyl)phenyl)boronic acid (CAS 1431616-41-9)
- Semaglutide Impurity 144 (CAS 394210-59-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com