Lamotrigine CAS 84057-84-1
| CAS No. | 84057-84-1 |
| Molecular Formula | C9H7Cl2N5 |
| Molecular Weight | 256.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Lamotrigine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Lamotrigine (CAS 84057-84-1), molecular formula C9H7Cl2N5 and molecular weight 256.09 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, Lamotrigine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 256.09 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Lamotrigine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7Cl2N5 |
| Molecular Weight | 256.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Lamotrigine Standards
- Lamotrigine 6-(3,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine Impurity (CAS 36518-85-1)
- Lamotrigine EP Impurity B and Lamotrigine EP Impurity C (CAS 84689-20-3)
- Lamotrigine Impurity 10 (CAS 77668-43-0)
- Lamotrigine Impurity 2 (CAS 94266-27-0)
- Lamotrigine EP Impurity B (CAS 94213-24-8)
- Lamotrigine EP Impurity G (CAS 38943-76-9)
- Lamotrigine EP Impurity C (CAS 94213-23-7)
- Lamotrigine Impurity 15 (CAS 1373393-59-9)
Recommended Standards
- Irsogladine Impurity 8 (CAS CATO-C4X-29148)
- n-Allyl-5-bromo-2-hydroxybenzamide (CAS 1007632-42-9)
- Irsogladine Impurity 7 (CAS CATO-C4X-29147)
- 4-((4-Bromo-1H-pyrazol-1-yl)methyl)-3,5-dimethylisoxazole (CAS 1011349-23-7)
- (1r)-1-(4-Bromo-3-methylphenyl)ethan-1-amine hydrochloride (CAS 2225126-87-2)
- 4-(3-Methyl-1,2,4-oxadiazol-5-yl)benzaldehyde (CAS 876316-27-7)
- Di-tert-butyl (((4-methoxyphenyl)thio)carbonyl)-L-glutamate (CAS 192203-59-1)
- 1-Chloro-3-(1,1-difluoroethyl)benzene (CAS 1204295-57-7)
- Tert-butyl ((3,5-dioxocyclohexyl)methyl)carbamate (CAS 1367772-68-6)
- 4-chloro-3-(pyrrolidin-1-yl)phenol (CAS 925233-11-0)
- Dexamethasone-d4 (CAS 50-02-2(Unlabelled))
- 9-(Phenylmethoxy)-nonanal (CAS 157730-78-4)
- Zinc nitrate hexahydrate (CAS 10196-18-6)
- Allo-D-Ile12-Tirzepatide (CAS CATO-CPTD788963)
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