Methyl 2-(5-chloro-2-nitrophenyl)-2-cyanoacetate CAS 389571-34-0
| CAS No. | 389571-34-0 |
| Molecular Formula | C10H7ClN2O4 |
| Molecular Weight | 254.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 254.63 g/mol gives Methyl 2-(5-chloro-2-nitrophenyl)-2-cyanoacetate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Methyl 2-(5-chloro-2-nitrophenyl)-2-cyanoacetate (CAS 389571-34-0) is a high-purity analytical reference standard with the molecular formula C10H7ClN2O4 and a molecular weight of 254.63 g/mol.
The molecular framework of Methyl 2-(5-chloro-2-nitrophenyl)-2-cyanoacetate (C10H7ClN2O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 2-(5-chloro-2-nitrophenyl)-2-cyanoacetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7ClN2O4 |
| Molecular Weight | 254.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 5-Chloro-2-methoxy-4-(1h-1,2,3,4-tetrazol-1-yl)benzoic acid (CAS 926268-74-8)
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- 3-Amino-1-(2-chloro-5-nitrophenyl)-1H-pyrazol-5(4H)-one (CAS 96701-60-9)
- 3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)propan-1-amine (CAS 101660-75-7)
- (R)-2-Methylazetidine Hydrochloride (CAS 791614-71-6)
- n-(3-Bromobenzyl)cyclopropanamine (CAS 892570-95-5)
- N-(3-Amino-5-oxo-4,5-dihydro-1H-pyrazol-4-yl)acetamide (CAS 99419-10-0)
- Mirogabalin Acyle Glucuronide (CAS CATO-CP155156)
- 3-Sulfamoyl-butyric acid methyl ester (CAS 1316222-19-1)
- (1s)-2-Fluoro-1-(2-fluorophenyl)ethan-1-ol (CAS 1932810-92-8)
- 3-Ethyl-3-hydroxypentanoic acid (CAS 58888-77-0)
- 1-Methyl-2,3-diphenylimidazolidine (CAS 146980-87-2)
- N-(Cyclohex-1-en-1-yl)formamide (CAS 40652-40-2)
- Ac, Gastrin Releasing Peptide (20-27), porcine (CAS 77714-20-6)
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