2-Chloro-1-(3-chloro-4-hydroxyphenyl)ethan-1-one CAS 39066-18-7
| CAS No. | 39066-18-7 |
| Molecular Formula | C8H6Cl2O2 |
| Molecular Weight | 205.04 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
2-Chloro-1-(3-chloro-4-hydroxyphenyl)ethan-1-one (CAS 39066-18-7) is a certified pharmaceutical impurity reference standard with the molecular formula C8H6Cl2O2 and a molecular weight of 205.04 g/mol.
2-Chloro-1-(3-chloro-4-hydroxyphenyl)ethan-1-one (C8H6Cl2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 2-Chloro-1-(3-chloro-4-hydroxyphenyl)ethan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6Cl2O2 |
| Molecular Weight | 205.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Cl-containing |
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Recommended Standards
- 2-Amino-4,5-dichlorobenzamide (CAS 952737-77-8)
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- 2-Chlorobenzyl carbonochloridate (CAS 39545-31-8)
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- 2-(3-(Hydroxymethyl)-1-methyl-1H-pyrazol-5-yl)acetonitrile (CAS 2853613-30-4)
- 1-(2-Chloro-3-(difluoromethoxy)phenyl)propan-1-one (CAS 1261821-25-3)
- tert-Butyl 3-fluoro-4-formylbenzoate (CAS 866625-12-9)
- Potassium (3-chloro-5-methoxyphenyl)trifluoroborate (CAS 929626-23-3)
- Methyl 3,4-diiodo-1-methyl-1h-pyrazole-5-carboxylate (CAS 75092-27-2)
- 1'-Methyl-[1,4'-bipiperidine]-3-carboxylic acid dihydrochloride (CAS 1185295-92-4)
- (D-Trp32)-Neuropeptide Y (porcine) trifluoroacetate salt (CAS 153549-78-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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