Vortioxetine Impurity 12 HBr CAS CATO-C4X-105612
| CAS No. | CATO-C4X-105612 |
| Molecular Formula | C18H22N2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 379.36 g/mol gives Vortioxetine Impurity 12 HBr distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Vortioxetine Impurity 12 HBr (CAS CATO-C4X-105612), a pharmacopoeial impurity reference standard (molecular formula C18H22N2SHBr, MW 379.36 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Vortioxetine Impurity 12 HBr (C18H22N2SHBr) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H22N2S HBr |
| Molecular Weight | 379.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Vortioxetine Standards
- Vortioxetine Impurity 63 (CAS 1009-85-4)
- Vortioxetine Impurity 2 (CAS 1011-13-8)
- Vortioxetine Impurity 89 (CAS 1019453-85-0)
- Vortioxetine Impurity 116 (CAS 102439-46-3)
- Vortioxetine Impurity 88 (CAS 103-19-5)
- Vortioxetine Impurity 60 (CAS 1049755-55-6)
- Vortioxetine Impurity 48 (CAS 105456-67-5)
- Vortioxetine Impurity 101 (CAS 107832-66-6)
Recommended Standards
- Dapagliflozin Impurity 187 (CAS CATO-C4X-1138187)
- Triptorelin Impurity 4 (CAS CATO-C4X-18624)
- Abemaciclib Impurity 157 (CAS CATO-C4X-2937157)
- 5-(2-(Bromomethyl)butyl)-1-methyl-1h-1,2,4-triazole (CAS 1493123-15-1)
- 2-(4-Chlorophenyl)-7-ethoxy-5-(4-nitrophenyl)-3H-benzo[e][1,2,4]triazepine (CAS 444159-02-8)
- Isoniazid EP Impurity D (CAS 553-53-7)
- Dapagliflozin Impurity 198 (CAS 2454263-77-3)
- 4-{6-[(oxan-4-yl)amino]imidazo[1,2-b]pyridazin-3-yl}benzene-1-sulfonamide (CAS 1012345-93-5)
- N-ethyltoluenesulfonamide (CAS 26914-52-3)
- Semaglutide impurity 83 (CAS CATO-C4X-222683)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com