(1E)-1-(Thiophen-2-yl)-N-[4-(trifluoromethoxy)phenyl]methanimine CAS 390788-29-1

Purity 97%+In StockPharmaceutical Standards
CAS No.390788-29-1
Molecular FormulaC12H8F3NOS
Molecular Weight271.26 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(1E)-1-(Thiophen-2-yl)-N-[4-(trifluoromethoxy)phenyl]methanimine CAS 390788-29-1 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (1E)-1-(Thiophen-2-yl)-N-[4-(trifluoromethoxy)phenyl]methanimine.

(1E)-1-(Thiophen-2-yl)-N-[4-(trifluoromethoxy)phenyl]methanimine (CAS 390788-29-1), molecular formula C12H8F3NOS and molecular weight 271.26 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution, (1E)-1-(Thiophen-2-yl)-N-[4-(trifluoromethoxy)phenyl]methanimine is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 271.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H8F3NOS
Molecular Weight271.26 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms1
Sulfur Atoms1

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